Analeptic Action of Anibine

Potential utilization of Brazilian wood extractives

“…4-Methoxypbenyleomnalin (Figure 4, 1), the simplest of the pyrones, remarkably has a nitrogenous analogue in anibine (Figure 4, 2), where the phenyl substituent is replaced by /3-pyridyl (Mors et al, 1957). Anibine itself was shown to have analeptic properties (Gonsalves et al, 1958) and its camphosulfonate has been patented for use as an antispasmodic agent in the treatment of heart and respiratory failure, as well as in comatose conditions induced by morphine and barbiturates (Boissier and Combes, 1964).…”