Anaesthetic management of the child with sickle cell disease

Marchant, Warwick; Walker, Isabeau

doi:10.1046/j.1460-9592.2003.01026.x

Cited by 52 publications

(55 citation statements)

References 104 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Therefore, endoscopic retrograde cholangiopancreatography (ERCP) was never indicated at the original presentation. The mean age of the patients was 13.2 years (range, [8][9][10][11][12][13][14][15][16]. We proposed an elective LC to all patients before the onset of symptoms.…”

mentioning

confidence: 99%

Laparoscopic cholecystectomy in children with chronic hemolytic anemia

et al. 2005

View full text Add to dashboard Cite

show abstract

mentioning

confidence: 99%

Laparoscopic cholecystectomy in children with chronic hemolytic anemia

et al. 2005

View full text Add to dashboard Cite

show abstract

“…Published guidelines on the preoperative evaluation and preparation of pediatric patients make no definite recommendations for sickle cell screening, 9 and this issue has received little attention in recent comprehensive reviews of the anesthetic management of sickle cell disease. 10,11 The Hospital for Sick Children, Toronto, serves a population of diverse ethnicity. Preoperative screening for sickle cell disease at this hospital has traditionally been at the discretion of individual clinicians.…”

Section: Resultsmentioning

confidence: 99%

“…Sickle cell disease is associated with significant perioperative morbidity, although reported complication rates are low for minor elective surgery and perioperative mortality is rare in patients younger than 14 yr. 15,16 Risk factors for perioperative morbidity -type of surgery, increasing age, frequency and severity of crises, pulmonary disease, and organ failure 10 -are assessable by review of the clinical history. Perioperative complication rates are similar for SS and SC disease, although the latter typically has a milder clinical phenotype.…”

Section: Discussionmentioning

confidence: 99%

Preoperative screening for sickle cell disease in children: clinical implications

Crawford

Galton

Abdelhaleem

2005

Can J Anesth/J Can Anesth

View full text Add to dashboard Cite

Purpose: Preoperative screening of at-risk patients for sickle cell disease (SCD) is recommended as a method to decrease perioperative morbidity. However, the effectiveness of preoperative screening in accomplishing this goal has never been demonstrated. We undertook a retrospective study to determine the prevalence of positive test results among those screened preoperatively at our institution and to determine whether amendments to present screening guidelines can be recommended. Methods:The hematology laboratory database of a university teaching hospital was searched to identify all patients who underwent preoperative screening for SCD from October 1999 to October 2003. The medical records of those patients testing positive were reviewed.Results: Of 1,906 children screened preoperatively, 79 (4.1%) were diagnosed as having sickle cell trait and three (0.16%) as having some form of SCD: one had homozygous hemoglobin S and two had sickle-hemoglobin C disease. Two of the three had a family history for SCD and none had a preoperative hemoglobin concentration < 10 g·dL -1. No patient developed perioperative sickle-related complications. Conclusion:Preoperative screening of 1,906 children identified only one asymptomatic child with undiagnosed SCD and a negative family history, suggesting that routine preoperative screening for SCD is rarely of significant clinical value in our population. Had preoperative screening not been performed, no child requiring preoperative transfusion would have been missed, representing a long-run probability of at least 99.84% that no at-risk child would require transfusion. We recommend that preoperative screening for SCD be undertaken selectively, giving consideration to the risks and benefits of screening to the individual patient. Objectif

show abstract

“…Bu hastalarda riski azaltmak için operasyon öncesi transfüzyon yapılması ve sıvı dengesinin sağlanması faydalı olabilmektedir. 28 …”

Section: Tani Ve Tedavi̇unclassified