Anaesthetic management in patients with high-risk Brugada syndrome

Hayashida, Hideaki; Miyauchi, Yosuke

doi:10.1093/bja/ael127

Cited by 22 publications

(22 citation statements)

References 4 publications

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“…[29] As an anticholinesterase agent, neostigmine is also avoided because it can lead to ST-segment elevation in BS patients. [54] Nevertheless, neostigmine [27,31,37,44,45] was the most frequently chosen agent in our cases to reverse the effects of NMBAs. Hayashida et al [54] applied as much as half of a normal dose of neostigmine with atropine for the purpose of ST-segment depression due to the effect of atropine.…”

Section: Dischargedmentioning

confidence: 86%

“…Our patients also received the NMBAs vecuronium, [27,29,34,35,43,45,46,54] rocuronium, [30][31][32][33]36] cisatracurium, [28,47] succinylcholine, [27,38,45] and atracurium [37,38,48] but succinylcholine is not normally used because of its adverse effects. [29] As an anticholinesterase agent, neostigmine is also avoided because it can lead to ST-segment elevation in BS patients.…”

Section: Dischargedmentioning

confidence: 99%

“…However, concerns about neostigmine have led some authors to prefer sugammadex, which was used safely in two of the reported cases. [30,36] Additionally, we found that atropine was selected for use in only one case [54] and that glycopyrrolate [27,31,45,48] was more commonly applied as an anticholinergic agent.…”

Section: Dischargedmentioning

confidence: 99%

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Brugada syndrome and anesthesia

Öztürk¹

2013

Turk Gogus Kalp Dama

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Brugada sendromu, yapısal kalp hastalığı bulunmayanlarda, elektrokardiyografide V1-3 derivasyonlarında sağ dal bloku ile spontan ya da indüklenmiş ST-segment elevasyonu ile karakterize, ani kardiyak ölüme yol açan genetik bir hastalıktır. Brugada sendromu bulunan hastalarda anestezi uygulamasına ilişkin sınırlı sayıda deneyim mevcut olduğu için, klinik uygulamaya yönelik henüz bir uzlaşı raporu bulunmamaktadır. Bu sistematik derlemede nadir görülen bu kalp hastalığında uygulanan anestezi teknikleri ve anesteziklerin etkileri ve güvenliliği irdelendi.Anah tar söz cük ler: Anestezi; anestezik ilaç; Brugada sendromu.Brugada syndrome is a genetic disease leading to sudden cardiac death, which is characterized by a spontaneous or induced ST-segment elevation with right bundle branch block in V1-3 leads in electrocardiography in those without any structural heart disease. As there is a limited number of experiences on anesthetizing patients with Brugada syndrome, no consensus report for clinical practice has been available yet. In this systematic review, we discussed the anesthesia techniques, and the effects and safety of anesthesia applied in this rarely seen heart disease.

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Section: Dischargedmentioning

confidence: 86%

Section: Dischargedmentioning

confidence: 99%

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Brugada syndrome and anesthesia

Öztürk¹

2013

Turk Gogus Kalp Dama

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“…Among volatile anesthetics, sevoflurane is the one of choice, as it provides greater QT interval stability [13,14]. There are described cases in which isoflurane and desflurane have been used without incident [15,16].…”

Section: Inhalational Anestheticsmentioning

confidence: 99%

“…In terms of blockade reversal, neostigmine has been used safely in many cases [13], however it should be avoided because it can increase ST segment elevation [17]. In our case, we used sugammadex, a γ-cyclodextrin with a lipophilic core that encapsulates rocuronium and vecuronium molecules, forging water-soluble complexes that are excreted in urine.…”

Section: Neuromuscular-blocking Drugs and Anticholinergicsmentioning

confidence: 99%

Brugada Syndrome: Management and Anaesthetic Implications: A Case Report

Esteve¹,

Cuquerella²,

Resalt³

et al. 2017

J Clin Case Rep

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Brugada syndrome (BrS) is a genetically determined disorder and has an autosomal dominant pattern of transmission, with incomplete penetrance and variable expression. These alterations may predispose to the development of reentrant arrhythmias, and therefore cause ventricular tachycardia and ventricular fibrillation. Patients may be asymptomatic, but they are prone to develop ventricular tachycardia or ventricular fibrillation and sudden death. Many events that occur during general anesthesia, such as drugs, temperature changes, and heart rate variations, may precipitate lethal arrhythmias in these patients. Thus, an individual anesthetic plan, taking into consideration the drugs that may induce arrhythmias, must be arranged before the surgery. Furthermore, it is essential to provide an exhaustive monitoring during the entire perioperative period. We describe a case of general anesthesia in a patient with Brugada syndrome who was diagnosed with right colon neoplasia and programmed for scheduled right hemicolectomy by laparotomy.

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