Anaesthesia and allergic drug reactions

Moudgil, G. C.

doi:10.1007/bf03010757

Cited by 14 publications

(3 citation statements)

References 63 publications

(6 reference statements)

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“…The management and investigation of allergic drug reactions during anaesthesia have recently been reviewed. 19,20 This case report underlines the need to investigate the role of materials as well as drugs in the aetiology of anaphylaxis. Latex is a newly recognized allergen.…”

Section: Discussionmentioning

confidence: 88%

Intraoperative anaphylaxis to latex

et al. 1990

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Section: Discussionmentioning

confidence: 88%

Intraoperative anaphylaxis to latex

et al. 1990

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“…Cutaneous manifestations such as erythema and rashes are the result of histamine-provoked capillary dilation and would disappear in few hours to few days after administration of antihistamines and corticosteroids. [7] Tachycardia, hypotension, and bronchospasm are the first signs of systemic reaction and anaphylaxis. Cardiovascular collapse can occur if anaphylaxis remains untreated.…”

Section: Discussionmentioning

confidence: 99%

Allergic reaction to intravenous atropine in a patient with organophosphate poisoning

et al. 2019

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Atropine is a drug of choice for muscarinic effects in organophosphate (OP) poisoning. Allergic reaction to atropine is rare. Here, we report a case of a 17-year-old male who was admitted with clinical manifestations of acute OP poisoning. After intravenous atropine injection, cutaneous signs of hypersensitivity including erythema and urticarial were observed on his body. Atropine injection was stopped, and antihistamines and hydrocortisone were administered. His condition was improved, and he discharged with a good condition after 2 days hospitalization. Adverse allergic reaction to atropine should be in mind when managing OP poisoning cases.

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“…We chose to pre-treat our patients with steroids, together with HI and H2 receptor antagonists. These drugs are recommended by Moudgil in his review of anaesthesia and allergic drug reactions 23 , and by others 24 following successful surgery and anaesthesia in a patient with a history of latex allergy. However, Weiss suggests that pre-treatment may mask early signs of anaphylaxis l9 and therefore does not recommend their use.…”

Section: Discussionmentioning

confidence: 99%