Abstract. Sustainable development is the projected demand of all nations at present. Only 20 percent of world's primary energy requirement is met by renewable sources like solar and wind energy, hydropower, bio mass, municipal and agri-wastes. Bio mass, can be utilized to produce biogas due to its high biodegradability, calorific value and nutritive value to microbes, which will reduce our dependency on fossil fuels so that These organic wastes require being managed in a sustainable way to avoid depletion of natural resources, minimize risk to hu man health, reduce environmental burdens and maintain an overall balance in the ecosystem. The annal of the Nat ional Office of Statistics (NOS) indicated that municipal solid waste overtook more and more million tons in 2016, almost 3.5 times the 1992 rates. About 40-70% of civilian solid waste CSW is composed of civilian bio mass waste (CBW), such as kitchen waste (KW), fru it/vegetable remains (FVR) and waste water sewage sludge (WWSS). There was a need to find several ways to deal with such wastes. One of these methods is the anaerobic digestion process, as a waste management system, has risen due to it has the usefulness of lowering volume and getting back energy. Several physical and chemical factors influence the creation of methane, and inhibition of bio-methane efficiency by certain materials (salts, oils, ammonia and toxic substrates ) may take p lace when inhibitors levels appear in high concentrations. In addition, high salt in the organic substrates can inhibit the activity of fermentation microbes by impacting the osmotic pressure of the cell wall of bacteria in the anaerobic system. The purpose of this study was to discuss the effect the types of substrates and salt content on biogas generation in anaerobic digestion.