Anaemia impedes functional mobility after hip fracture surgery

Foss, Nicolai Bang; Kristensen, Morten Tange; Kehlet, Henrik

doi:10.1093/ageing/afm161

Cited by 208 publications

(180 citation statements)

References 19 publications

Supporting

Mentioning

154

Contrasting

Unclassified

Order By: Relevance

“…Readmission to hospital was associated with anaemia in one study, up to 90 days after discharge [40], but anaemia was not associated with readmission up to 28 days after discharge in a second study [35]. Three studies reported no association of anaemia with postoperative complications [19,20,22] and one did [21]. Two studies reported an association between anaemia and reduced function [20,29], but two studies did not when adjusted for other factors [27,30].…”

Section: Methodsmentioning

confidence: 99%

A systematic review of pre-operative anaemia and blood transfusion in patients with fractured hips

2015

View full text Add to dashboard Cite

SummaryWe systematically reviewed the observational associations of anaemia with outcomes and the effects of interventions to increase haemoglobin concentrations following hip fracture in older people. Anaemia on hospital admission was associated with increased mortality, relative risk 1.64 (95% CI 1.47-1.82), p < 0.0001. After adjustment for co-morbidities, the association of anaemia with increased mortality remained in four of eight observational studies. There was no association of postoperative transfusion with mortality after adjusting for covariates. Transfusion at 80 g.l À1 vs 100 g.l À1 increased acute myocardial infarction, relative risk 1.67 (95% CI 1.01-2.77), p = 0.05. Transfusion threshold was not associated with differences in other outcomes. There were insufficient high-quality studies to inform pre-operative blood transfusion or the use of peri-operative iron or erythropoietin. Studies for most interventions recruited too few participants to determine effects on infections, mortality or function.

show abstract

Section: Methodsmentioning

confidence: 99%

A systematic review of pre-operative anaemia and blood transfusion in patients with fractured hips

2015

View full text Add to dashboard Cite

show abstract

“…A large number of research has been done to investigate the impact of different variables on recovery after hip fracture surgery [8][9][10]. The effect of perioperative anemia on surgical mortality and morbidity in hip fracture patients has also been addressed in literature [11][12][13][14]. However, a limited number of studies have investigated the relationship between admission hemoglobin level and hip fracture outcome [15][16][17].…”

Section: Introductionmentioning

confidence: 99%

Is anemia at admission related to short-term outcomes of elderly hip fracture patients?

Dubljanin-Raspopovic¹,

Marković-Denić

Nikolić

et al. 2011

Open Medicine

View full text Add to dashboard Cite

AbstractHip fracture in elderly people is associated with high morbidity and mortality. Therefore, it is important to identify risk factors that potentially influence outcomes after hip surgery. The main purpose of this study was to evaluate the relationship of anemia at admission and short-term outcomes after hip fracture. We studied 343 community-dwelling patients who underwent surgery for hip fracture from March 2009 to March 2010. Functional mobility at discharge, postoperative complications, hospital length of stay and in-hospital mortality were analyzed in respect to presence and severity of anemia at admission. Anemia (defined as hemoglobin levels < 13.0 g/dl for men and < 12.0g/dl for women) was present in 185 (53.9%) patients, of whom 54 (29.2%) were severely anemic (defined as hemoglobin level 10.0g/dl or below). In multivariate analysis anemia was associated with age, gender (female), type of fracture (intertrochanteric) and American Society of Anesthesiologists (ASA) classification (3 or 4), while severity of anemia was associated with recovery of ambulatory ability at discharge. There was no difference in the incidence of postoperative complication, in-hospital mortality and length of hospital stay between the groups at discharge. Overall anemia at admission is an indicator of poor general health status. Ambulatory recovery in hip fracture patients is independently related to severity of anemia at admission.

show abstract

“…3 17 18 In addition to mortality, preoperative anaemia is also significantly and independently associated with increased morbidity, including the elevated risk of infectious complications and a prolongation of postoperative hospital stay. 14 -16 19 Some studies have linked perioperative anaemia to impaired postoperative functional recovery after surgery for hip fracture, 15 16 20 although it was not an independent factor in a prospective multivariate analysis. 16 In addition, anaemia is a risk factor for both early and late mortality in patients undergoing coronary artery bypass grafting (CABG).…”

mentioning

confidence: 99%