An Updated Reappraisal of Dupilumab in Children and Adolescents with Severe Asthma
Gian Luigi Marseglia,
Amelia Licari,
Maria Angela Tosca
et al.
Abstract:Severe asthma (SA) is still a demanding challenge in clinical practice. Type 2 inflammation is the most common phenotype in children and adolescents with SA. As a result, anti-inflammatory drugs, mainly corticosteroids (CSs), represent the first choice to reduce type 2 inflammation. However, SA patients may require high inhaled and oral CS doses to achieve and maintain asthma control. Some SA patients, despite the highest CS dosages, can even display uncontrolled asthma. Therefore, the biological era constitut… Show more
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