An update on the current understanding of the infant skin microbiome and research challenges

Serghiou, Iliana R; Webber, Mark A.; Hall, Lindsay J.

doi:10.1016/j.mib.2023.102364

Cited by 2 publications

(1 citation statement)

References 43 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…When studying neonatal skin microbiota, skin swab samples are gathered from infant skin sites, including the forehead, posterior auricular scalp, periumbilical region, inguinal folds, upper thighs, and oral cavity. These samples are then transported to the laboratory for further analysis, which may involve DNA extraction and sequencing to elucidate the neonatal skin microbiota's microbial diversity and composition [ 12 , 45 ]. Overall, non-invasive methods such as skin swabbing are favored for studying the neonatal skin microbiota due to their simplicity, non-invasiveness, and suitability for large-scale sampling.…”

Section: Reviewmentioning

confidence: 99%

Exploring the Microbial Landscape of Neonatal Skin Flora: A Comprehensive Review

Jain,

Meshram,

Lohiya

et al. 2024

Cureus

View full text Add to dashboard Cite

This comprehensive review explores the intricate landscape of the neonatal skin microbiome, shedding light on its dynamic composition, developmental nuances, and influential factors. The neonatal period represents a critical window during which microbial colonization significantly impacts local skin health and the foundational development of the immune system. Factors such as mode of delivery and gestational age underscore the vulnerability of neonates to disruptions in microbial establishment. Key findings emphasize the broader systemic implications of the neonatal skin microbiome, extending beyond immediate health outcomes to influence susceptibility to infections, allergies, and immune-related disorders. This review advocates for a paradigm shift in neonatal care, proposing strategies to preserve and promote a healthy skin microbiome for long-term health benefits. The implications of this research extend to public health, where interventions targeting the neonatal skin microbiome could potentially mitigate diseases originating in early life. As we navigate the intersection of research and practical applications, bridging the gap between knowledge and implementation becomes imperative for translating these findings into evidence-based practices and improving neonatal well-being on a broader scale.

show abstract

Section: Reviewmentioning

confidence: 99%