An update on the current management of adult obstructive sleep apnoea

Sarkissian, Lernik; Kitipornchai, Leon; Cistulli, Peter A.; MacKay, Stuart

doi:10.31128/ajgp-10-18-4749

Cited by 11 publications

(7 citation statements)

References 45 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…For OSA in children, therapeutic alternatives include surgical options, such as adentonsillectomy as first line treatment for OSA; early adenotonsillectomy has been shown to reduce symptoms of OSA and improve behavior, quality of life, and PSG findings 93 . In adults, treatment options for OSA include oral mandibular advancement devices, hypoglossal nerve stimulation, myofunctional therapy and positional devices 94‐96 . Pharmacologic therapies for OSA, such as montelukast and nasal steroids have shown mixed results in pediatric and adult populations, with some benefit to montelukast being seen in children but not adults 97,98 …”

Section: Treatmentmentioning

confidence: 99%

Sleep‐disordered breathing in cystic fibrosis

Jagpal

Jobanputra

Ahmed

et al. 2021

Pediatric Pulmonology

View full text Add to dashboard Cite

Sleep‐disordered breathing (SDB) is an under recognized comorbidity in the cystic fibrosis (CF) population across the lifespan. Nocturnal hypoxemia, obstructive sleep apnea, and nocturnal hypoventilation are respiratory abnormalities that occur commonly during sleep in patients with lung disease, and have deleterious consequences to the quality of life in people with CF. Effective screening for these abnormalities is needed to allow for timely initiation of treatment, which has been reported to be efficacious. Lack of treatment leads to worsened pulmonary, cardiovascular, and metabolic outcomes in patients. In this review, we give an overview of SDB for the CF clinician, including prevalence, treatment, and suggestions for future research. We strongly encourage the CF community to incorporate evaluation for SDB in CF clinical care so that outcomes for the subset of the CF patients with comorbid SDB improve.

show abstract

Section: Treatmentmentioning

confidence: 99%

Sleep‐disordered breathing in cystic fibrosis

Jagpal

Jobanputra

Ahmed

et al. 2021

Pediatric Pulmonology

View full text Add to dashboard Cite

show abstract

“…In children, therapeutic options include surgical options such adentonsillectomy as first line treatment for OSA. Additional options for OSA in adults include oral devices, glossopharyngeal nerve stimulation, myofunctional therapy and positional devices [58][59][60] . Pharmacologic therapies for OSA, such as montelukast and nasal steroids have shown mixed results in pediatric and adult populations, with some benefit to montelukast being seen in children but not adults 61,62 .…”

Section: Treatmentmentioning

confidence: 99%

Sleep- Disordered Breathing in Cystic Fibrosis

Jobanputra

Jagpal

Ahmed

et al. 2020

Preprint

View full text Add to dashboard Cite

Sleep-disordered breathing is an underrecognized comorbidity in the cystic fibrosis (CF) population across the lifespan. Nocturnal hypoxia, obstructive sleep apnea (OSA), and nocturnal hypoventilation are respiratory abnormalities that occur commonly during sleep, and have deleterious consequences to quality of life in people with CF. Effective screening for these abnormalities is needed to allow for the timely initiation of treatment. Lack of treatment leads to worse pulmonary, cardiovascular, and metabolic outcomes in patients. In this review, we give an overview of sleep-disordered breathing for the CF clinician, including definitions, treatment, and suggestions for future research. We strongly encourage the CF community to incorporate evaluation for sleep-disordered breathing, so that outcomes for the subset of the patients with coexisting sleep-disordered breathing improve.

show abstract

“…In addition, nose and upper airway/maxillary-mandibular deficiencies are corrected by otorhinolaryngology and maxillofacial surgeons and obesity by bariatric surgeons. Hence, there are no stand-alone treatments for OSA (Almoznino et al 2017; Lorenzi-Filho et al 2017; Schwartz et al 2018; Sarkissian et al 2019).…”

Section: Osa Management: Diagnosis Treatment and Follow-upmentioning

confidence: 99%

Critical Issues in Dental and Medical Management of Obstructive Sleep Apnea

et al. 2019

View full text Add to dashboard Cite

This critical review focuses on obstructive sleep apnea (OSA) and its management from a dental medicine perspective. OSA is characterized by ≥10-s cessation of breathing (apnea) or reduction in airflow (hypopnea) ≥5 times per hour with a drop in oxygen and/or rise in carbon dioxide. It can be associated with sleepiness and fatigue, impaired mood and cognition, cardiometabolic complications, and risk for transportation and work accidents. Although sleep apnea is diagnosed by a sleep physician, its management is interdisciplinary. The dentist’s role includes 1) screening patients for OSA risk factors (e.g., retrognathia, high arched palate, enlarged tonsils or tongue, enlarged tori, high Mallampati score, poor sleep, supine sleep position, obesity, hypertension, morning headache or orofacial pain, bruxism); 2) referring to an appropriate health professional as indicated; and 3) providing oral appliance therapy followed by regular dental and sleep medical follow-up. In addition to the device features and provider expertise, anatomic, behavioral, demographic, and neurophysiologic characteristics can influence oral appliance effectiveness in managing OSA. Therefore, OSA treatment should be tailored to each patient individually. This review highlights some of the putative action mechanisms related to oral appliance effectiveness and proposes future research directions.

show abstract

An update on the current management of adult obstructive sleep apnoea

Cited by 11 publications

References 45 publications

Sleep‐disordered breathing in cystic fibrosis

Sleep‐disordered breathing in cystic fibrosis

Sleep- Disordered Breathing in Cystic Fibrosis

Critical Issues in Dental and Medical Management of Obstructive Sleep Apnea

Contact Info

Product

Resources

About