An Update on Critical Congenital Heart Disease Screening Using Pulse Oximetry

Hom, Lisa A.; Martin, Gerard R.; Oster, Matthew E.

doi:10.1007/s40124-016-0095-2

Cited by 2 publications

(2 citation statements)

References 45 publications

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“…This result is similar to the previously reported literature in which the New Jersey algorithm demonstrated a slight increase in the number of false-positive cases. 18 Based on these conclusions, we suspect that there are other elements in the screening practice that have yet to be described, and which may have influenced the false-positive rate, more than the algorithm itself.…”

Section: Retrospective Studymentioning

confidence: 97%

“…Even small differences in these indicators greatly impact the workload of and follow-up by healthcare practitioners. 18 Screening by pulse oximetry is a promising strategy; however, important decisions still need to be made to optimise screening, follow-up, and the associated steps necessary to confirm the diagnosis, as well as to increase the sensitivity and specificity of this approach for evaluation. Particularly, opportunities related to screening algorithm selection, peripheral oxygen saturation thresholds for different altitudes, medical practitioners' misinterpretation of the algorithm, data transfer to a central system, use of a reliable database, standardisation of operations, and other prospects for further expansion of the programmes have been reported.…”

Section: Introductionmentioning

confidence: 99%

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Critical CHD screening programme: a 3-year multicentre experience in Mexico

et al. 2022

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Introduction: CHDs are the most common type of birth defect. One in four newborns with a heart defect has a critical CHD. In Mexico, there is a lack of data available to determine its prevalence. Pulse oximetry screening programmes have been implemented worldwide, reporting opportunity areas in algorithm interpretation and data management. Our study aims to share preliminary results of a 3-year experience of a multicentre pulse oximetry screening programme that addresses critical challenges. Materials and methods: This retrospective study examined the reports of newborns screened from February 2016 to July 2019 from five hospitals. Two algorithms –the New Jersey and the American Academy of Pediatrics– were implemented over consecutive periods. The algorithms’ impact was assessed through the calculation of the false-positive rate in an eligible population. Results: A total of 8960 newborns were eligible for the study; from it, 32.27% were screened under the New Jersey and 67.72% under the American Academy of Pediatrics algorithm – false-positive rate: 1% (CI 95: ± 0.36%) and 0.71% (CI 95: ± 0.21%), respectively. Seventy-nine newborns were referred, six were diagnosed with critical CHD, and six with CHD. The critical CHD estimated prevalence was 6.69:10,000 newborns (CI 95: ± 5.36). Our results showed that the algorithm was not related to the observable false-positive rate reduction. Discussion: Other factors may play a role in decreasing the false-positive rate. Our experience implementing this programme was that a systematic screening process led to more confident results, newborn’s report interpretation, and follow-up.

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Section: Retrospective Studymentioning

confidence: 97%

Section: Introductionmentioning

confidence: 99%