An Unusual Source of Vibrio alginolyticus–Associated Otitis

Mukherji, Atreyi; Schroeder, Suzanne; Deyling, Cynthia; Procop, Gary W.

doi:10.1001/archotol.126.6.790

Cited by 19 publications

(4 citation statements)

References 4 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The reason for V. alginolyticus 's lack of virulence remains unclear. V. alginolyticus has been etiologically associated with cellulitis and acute otitis media or externa 3,6-10. As a whole, these infections have responded well to appropriate antibiotics.…”

Section: Discussionmentioning

confidence: 99%

Septic Shock due to Vibrio alginolyticus in a Cirrhotic Patient: The First Case in Korea

et al. 2008

View full text Add to dashboard Cite

We describe a case of septic shock due to Vibrio alginolyticus presenting with fever and bilateral leg pain. Despite intensive management with antibiotics and inotropic agents, the patient died from septic shock 1 day after hospitalization. V. alginolyticus was isolated from both leg wounds and a blood culture. To the best of our knowledge, this is the first reported case of V. alginolyticus bacteremia in Korea.

show abstract

Section: Discussionmentioning

confidence: 99%

Septic Shock due to Vibrio alginolyticus in a Cirrhotic Patient: The First Case in Korea

et al. 2008

View full text Add to dashboard Cite

show abstract

“…hydrophila and V. alginolyticus infections have been reported in association with wounds exposed to water. [3][4][5][6][7]14,16,17 However, the number of clinical reports and reviews concerning A. hydrophila or V. alginolyticus infections in clinical journals is limited. In this case, it was likely that both isolates of A. hydrophila and V. alginolyticus were originally associated with water in Hamana Lake, a brackishwater lake, in which fresh water from a river and sea water mix.…”

Section: Discussionmentioning

confidence: 99%

“…15 Human infections caused by V. alginolyticus include ear, soft tissue, and wound infections. 14,16,17 Recent reports 18 showed that 40% of V. alginolyticus isolated from the environment produce ␤-lactamases conferring resistance to ampicillin. Antibiotic resistance in V. alginolyticus is a significant problem for wound infections related to the aquatic environment.…”

mentioning

confidence: 99%

Antibiotic Resistance in Aeromonas hydrophila and Vibrio alginolyticus Isolated from a Wound Infection: A Case Report

Horii

Morita

Muramatsu

et al. 2005

The Journal of Trauma: Injury, Infection, and Critical Care

View full text Add to dashboard Cite

Aeromonas hydrophila is a motile, nonsporulating, fermentative, facultative, anaerobic, gram-negative bacillus commonly found in fresh water, tap water, soil, and swimming pools. 1,2 Human infections caused by Aeromonas spp. are frequently associated with trauma in the aquatic environment, 3-7 immunosuppression, 7 and chronic disease. 8 ␤-Lactam resistance in Aeromonas spp. has been reported. 9 In clinical Aeromonas isolates, genetic properties of the ␤-lactamase genes have been characterized. 9 -12 Previous reports 9,13 demonstrated that Aeromonas spp. can produce multiple ␤-lactamases, including a carbapenem-hydrolyzing metallo-␤-lactamase, which is an important problem for antibiotic treatment.Vibrio alginolyticus is a facultatively anaerobic, gramnegative bacillus with a single polar flagellum for mobility. 14 V. alginolyticus, a halophilic bacterium, is common in coastal waters and sediments all over the world. 15 Human infections caused by V. alginolyticus include ear, soft tissue, and wound infections. 14,16,17 Recent reports 18 showed that 40% of V. alginolyticus isolated from the environment produce ␤-lactamases conferring resistance to ampicillin. Antibiotic resistance in V. alginolyticus is a significant problem for wound infections related to the aquatic environment.We describe a wound infection caused by both A. hydrophila and V. alginolyticus related to an aquatic environment. Genetic analysis suggests that microbiologic examination is critical, because these aquatic environment-related isolates had a variety of determinants of antibiotic resistance. CASE REPORTA 37-year-old man had fallen out of a boat at Hamana Lake in Japan, twining his left fingers in a rope, and the left second and third digits were amputated in 2001. The amputated digits were exposed to the lake water for several minutes to an hour. He was admitted to a Hamamatsu city hospital. At admission, laboratory examination revealed a C-reactive protein concentration of 1 mg/L (normal, 0 -1 mg/L), a white blood cell count (WBC) of 12.9 ϫ 10 9 cells/L (normal, 3.5-8.9 ϫ 10 9 cells/L), and a platelet count of 281 ϫ 10 9 /L (normal, 147-332 ϫ 10 9 /L). After surgical treatment with replantation and stump plasty, intravenous cefazolin 2 g administered twice daily was started. However, the replantated fingers had necrosis and wound infection. On hospital day 12, the fingers were removed. Both A. hydrophila SHH-029 and V. alginolyticus SHH-031 were isolated from wound fluid collected on day 12. Then, antibiotic therapy was changed to intravenous imipenem 0.5 g administered twice daily. Laboratory examination revealed a C-reactive protein concentration of 57 mg/L, a white blood cell count of 12.1 ϫ 10 9 cells/L, and a platelet count of 456 ϫ 10 9 /L. Minimum inhibitory concentrations (MICs) were determined by the agar dilution method as described by the National Committee for Clinical Laboratory Standards. 19 Susceptibility testing was performed on Mueller-Hinton agar (Nippon Becton Dickinson, Tokyo, Japan). The results of susceptibility testi...

show abstract

“…Symptoms include diarrhea, abdominal cramps, vomiting, fever, and skin lesions if infection enters through a wound [ 2 , 3 ]. There have been a few reports of V. alginolyticus causing otitis externa in patients with recent exposure to infested seawater, primarily limited to waters around Europe or the Mediterranean in the warmer times of the year [ 4 , 5 ]. The suspected pathogenesis is that the strain exerts cytotoxic effects on keratinocytes and HEI-OC1 cells by inhibiting cell proliferation and migration and inducing apoptosis and cell death [ 6 ].…”

Section: Introductionmentioning

confidence: 99%

Vibrio alginolyticus: A Rare Cause of Otitis Externa off the Coast of Florida

Khan,

Linkous,

Lanza

2024

Cureus

View full text Add to dashboard Cite

Vibrio alginolyticus, a gram-negative marine bacterium, poses significant health risks through various infections transmitted via contaminated seawater or seafood consumption. This case report details a 42year-old male presenting with chronic seropurulent discharge from his ear, ultimately diagnosed with otitis externa caused by V. alginolyticus. Examination findings and antibiotic sensitivity testing informed the treatment strategy, leading to a successful resolution. The increasing incidence of V. alginolyticus infections, particularly in warm coastal water, necessitated heightened clinical awareness and appropriate management. As global temperatures rise, proactive measures including patient education and accurate diagnosis become crucial in preventing disease progression and complications associated with V. alginolyticus infections.

show abstract

An Unusual Source of Vibrio alginolyticus–Associated Otitis

Cited by 19 publications

References 4 publications

Septic Shock due to Vibrio alginolyticus in a Cirrhotic Patient: The First Case in Korea

Septic Shock due to Vibrio alginolyticus in a Cirrhotic Patient: The First Case in Korea

Antibiotic Resistance in Aeromonas hydrophila and Vibrio alginolyticus Isolated from a Wound Infection: A Case Report

Vibrio alginolyticus: A Rare Cause of Otitis Externa off the Coast of Florida

Contact Info

Product

Resources

About