An unusual sinonasal inverted papilloma originating from superior turbinate and extending to epiglottis

Abstract

Sinonasal inverted papillomas are benign tumors of the nasal cavity and paranasal sinuses. The basic characteristics of these papillomas are their different localizations in the nasal cavity, local aggressive behavior and potential to transform into malignant tumors. The most common symptoms of those tumors are nasal obstruction, rhinorrhea, and epistaxis. Rare symptoms such as dysphagia and hoarseness may be seen in relation with the localization and the size of the tumor. In this article, we present an unusual case of a huge inverted papilloma originating from the superior turbinate, extending down to epiglottis, and causing dysphagia and dyspnea.Keywords: Epiglottis; inverted papilloma; paranasal sinus.Schneiderian papillomas are neoplastic proliferations seen rarely in the nose and paranasal sinuses.[1] They have three histological subtypes--inverted, fungiform (exophytic) and oncocytic (cylindric). [1,2] Inverted and oncocytic forms usually originate from the lateral nasal wall, while the fungiform type is typically localized in the nasal septum. [3] Nasal obstruction is the most frequent presenting symptom in patients with sinonasal inverted papilloma (SIP). Epistaxis, rhinorrhea, and headache are less frequent.[4] Patients with SIP may present with atypical symptoms such as dysphagia, sensation of a lump in the throat, and hoarseness. In this case report, we present a SIP that originated from the superior turbinate, ÖZSinonazal inverted papillomlar, burun ve paranazal sinüslerin benign tümörleridir. Bu papillomların temel özellikleri; nazal kavite içinde farklı lokalizasyonlarda bulunabilmeleri, lokal agresif seyir göstermeleri ve malign tümörlere dönüşme potansiyelleridir. Burun tıkanıklığı, burun akıntısı ve burun kanaması bu tümörlerin en yaygın semptomlarıdır. Tümörün yerleşim yerine ve büyüklüğüne bağlı olarak, yutma güçlüğü ve ses kısıklığı gibi nadir semptomlara da rastlanabilir. Bu yazıda üst konkadan köken alan, epiglota kadar uzanan ve yutma güçlüğü ve nefes darlığına yol açan sıra dışı dev bir sinonazal inverted papillom olgusu sunuldu.Anahtar Sözcükler: Epiglot; inverted papillom, paranazal sinüs.Üst konkadan köken alan ve epiglota uzanan sıra dışı bir sinonazal inverted papillom

Value of a Multidisciplinary Approach in Sinonasal Inverted Papilloma with Extensive Ossification

“…Therefore, computed tomography (CT) scan of the facial bones has long been considered the criterion standard exam for primary diagnosis and follow-up [ 2 ]. Due to its invasiveness, its high degree of recurrence, and a possibility of malignant transformation [ 3 ], its treatment consists of radical surgery [ 4 ]. Although immunomodulatory therapies have increasingly emerged as a promising new treatment option for advanced malignancies, results from clinical studies of immune checkpoint modulating drugs in this setting have led to mixed results [ 5 – 8 ].…”