An Unusual Rash in a Five-Year-Old Girl: Blaschkoid Distribution Is the Key to the Diagnosis

Pediatric onychodystrophy: is it always a fungal infection?

“…Lichen striatus (LS) is a rare, benign, acquired dermatosis with a predilection for females [1][2][3][4][5] . The etiology is unknown, but it has been hypothesized to be derived from cutaneous mosaicism caused by a postzygotic somatic mutation 3,4 .…”

“…Lichen striatus (LS) is a rare, benign, acquired dermatosis with a predilection for females [1][2][3][4][5] . The etiology is unknown, but it has been hypothesized to be derived from cutaneous mosaicism caused by a postzygotic somatic mutation 3,4 . Triggering events such as trauma, viral infections, vaccinations, and medications, can initiate an autoimmune response 3,4 which will produce a linear dermatosis, characterized by pink to flesh-colored or erythematous, millimetric flat-topped papules that follow Blaschko's lines [1][2][3][4][5] .…”

“…The etiology is unknown, but it has been hypothesized to be derived from cutaneous mosaicism caused by a postzygotic somatic mutation 3,4 . Triggering events such as trauma, viral infections, vaccinations, and medications, can initiate an autoimmune response 3,4 which will produce a linear dermatosis, characterized by pink to flesh-colored or erythematous, millimetric flat-topped papules that follow Blaschko's lines [1][2][3][4][5] . Papules often coalesce to form a hyperpigmented continuous or interrupted linear band over weeks (occasionally months) 1,3 .…”

“…Triggering events such as trauma, viral infections, vaccinations, and medications, can initiate an autoimmune response 3,4 which will produce a linear dermatosis, characterized by pink to flesh-colored or erythematous, millimetric flat-topped papules that follow Blaschko's lines [1][2][3][4][5] . Papules often coalesce to form a hyperpigmented continuous or interrupted linear band over weeks (occasionally months) 1,3 . It is typically unilateral, most commonly involving the extremities with a proximal to distal progression [1][2][3] .…”

“…Papules often coalesce to form a hyperpigmented continuous or interrupted linear band over weeks (occasionally months) 1,3 . It is typically unilateral, most commonly involving the extremities with a proximal to distal progression [1][2][3] . Although rare, there is sometimes involvement of the nail leading to onychodystrophy, characterized by nail pitting, longitudinal ridging, nail plate thinning and subungual hyperkeratosis 1,4 .…”