An unusual presentation of alveolar haemorrhage

Román-Vélez, Jesús M; Martínez-Camacho, Ruth N; Alayón-Laguer, Diógenes; Fernández-González, Ricardo; Reyes-Sosa, Raul; Santos-Llanos, Glorimar; Colón-Pérez, Miguel; Ferrer, D

doi:10.4104/pcrj.2009.00049

Cited by 4 publications

(1 citation statement)

References 8 publications

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“…The results are presented in Table 1. A few cases were excluded due to the high probability of bias on account of unclear or missing data regarding immunosuppression or the diagnosis of severe strongyloidiasis: local corticosteroid injections [57], multiple myeloma in remission and corticosteroid treatment after hospital admission [58], possible untreated rheumatoid arthritis and short corticosteroid treatment after hospital admission [59], unclear corticoid treatment for asthma and emphysema [60], unclear asthma treatment [61], previous single-dose corticoid treatment [62], previously undiagnosed diabetes and short corticoid treatment after hospital admission [63], possible corticosteroid treatment and partial gastrectomy surgery [64], unclear severe strongyloidiasis diagnosis [65,66].…”

Section: Resultsmentioning

confidence: 99%

A Rare Case of Strongyloides stercoralis Hyperinfection in a Diabetic Patient from Romania—Case Report and Review of the Literature

et al. 2023

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Severe cases of strongyloidiasis are most often associated with multiple causes of immune suppression, such as corticoid treatment and HTLV (human T-lymphotropic virus) coinfection. Diabetes is not traditionally considered a risk factor for the development of severe strongyloidiasis. We report a rare case of autochthonous severe strongyloidiasis in Romania, a European country with a temperate climate. A 71-year-old patient with no prior travel history was admitted with multiple gastrointestinal complaints and recent weight loss. CT (computed tomography) scans indicated duodenal wall thickening, and duodenal endoscopy evidenced mucosal inflammation, ulcerations and partial duodenal obstruction at D4. Microscopic examination of stool samples and biopsy specimens from the gastric and duodenal mucosa revealed an increased larval burden characteristic of Strongyloides stercoralis hyperinfection. Sequential treatment with albendazole and ivermectin achieved parasitological cure and complete recovery. The novelty of our case stems from the scarcity of severe strongyloidiasis cases reported in Europe and especially in Romania, the absence of other risk factors in our patient aside from diabetes, the involvement of the gastric mucosa and the rare presentation as partial duodenal obstruction. This case highlights the importance of considering strongyloidiasis as a differential diagnosis, even in temperate climates where cases are sporadic, in cases in which immune suppression is not evident and in the absence of eosinophilia. The case is presented in the context of the first literature review examining the relationship between severe strongyloidiasis and diabetes, emphasizing diabetes as a possible risk factor for severe strongyloidiasis.

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Section: Resultsmentioning

confidence: 99%

A Rare Case of Strongyloides stercoralis Hyperinfection in a Diabetic Patient from Romania—Case Report and Review of the Literature

et al. 2023

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Parasitic Lung Infections

Timsit

Brion

Pelloux

2010

Pulmonary Involvement in Patients With Hematological Malignancies

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Imported Strongyloidiasis: Epidemiology, Presentations, and Treatment

Buonfrate

Angheben

Gobbi

et al. 2012

Curr Infect Dis Rep

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Strongyloidiasis is extremely more frequent in immigrants than in travellers. Clinical presentations do not differ significantly between the two groups, and the most frequent picture is a chronic infection characterized by intermittent, mild, non-specific symptoms. Acute presentation is rare but it has been reported in travellers. Screening of asymptomatic subjects is not generally recommended, while a presumptive treatment with ivermectin might be justified for all travellers and immigrant patients presenting unexplained eosinophilia and/or compatible symptoms, even in case of negative test results. In fact, delayed diagnosis and treatment has life-threatening consequences in patients with conditions predisposing to development of hyperinfection and dissemination.

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An unusual presentation of alveolar haemorrhage

Cited by 4 publications

References 8 publications

A Rare Case of Strongyloides stercoralis Hyperinfection in a Diabetic Patient from Romania—Case Report and Review of the Literature

A Rare Case of Strongyloides stercoralis Hyperinfection in a Diabetic Patient from Romania—Case Report and Review of the Literature

Parasitic Lung Infections

Imported Strongyloidiasis: Epidemiology, Presentations, and Treatment

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