An unusual occurrence of stromal keratitis in dengue fever

Bawankar, Pritam; Lahane, Tatyarao; Parekh, Ragini; Lahane, Sayalee; Lahane, Sumeet; Pathak, Pooja; Sonawane, Sayli

doi:10.4103/ijo.ijo_387_18

Cited by 6 publications

(5 citation statements)

References 5 publications

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“…Whereas, in our study, there was a current history of fever and the platelet levels were >60,000/µl. Bawankar et al reported a case of stromal keratitis in dengue fever, in a 25-year-old female [15]. The patient developed stromal keratitis 15 days post dengue fever.…”

Section: Discussionmentioning

confidence: 99%

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Ophthalmic manifestations as the first presenting feature in dengue fever: a 10-year study

2024

RJO

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Purpose: To report patients who first presented with various ocular manifestations and eventually ascertained to have underlying dengue. Methods: A prospective study was conducted at multiple tertiary eye-care centers in India from 2012 to 2022. Cases reporting initially with ocular features along with fever/past history of fever over the last two weeks or with clinical features of dengue were selected. After an ophthalmological examination, patients underwent complete serological and biochemical analysis and those with reduced platelet counts were evaluated for dengue. Results: Out of 564 cases, 15 patients were verified to be afflicted with dengue eventually. A rising trend of cases was seen every year and out of 15 cases, eight cases were reported during the Covid-19 pandemic (from 2020 to 2022), but were COVID-negative. 9 cases presented with acute redness followed by diminished vision. Seven cases presented a history of fever over the last few days and one had traveled from dengue endemic area. The various ocular presentations included subconjunctival hemorrhage, viral keratitis, anterior uveitis, sixth-nerve palsy, and vitreous hemorrhage. On serological examination, all 15 patients were detected to have low platelets. All cases responded well with supportive treatment and the ocular features subsided in all within a couple of weeks with good visual recovery. Conclusion: In a tropical nation, such as India, with endemic dengue zones and increasing figures of dengue lately, ophthalmologists must include dengue fever among the differential diagnoses in various ocular presentations like subconjunctival hemorrhage, viral keratitis, anterior uveitis, sixth nerve palsy, and vitreous hemorrhage. Abbreviations: DHF = dengue hemorrhagic fever, PCR = polymerase chain reaction, RT-PCR = real-time automated reverse transcriptase (RT-PCR), SD = standard deviation, MAC-ELIS = IgM antibodies capture enzyme-linked immunosorbent assay, RE = right eye, LE = left eye, CECT = Contrast-enhanced computed tomography

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Section: Discussionmentioning

confidence: 99%

“…Bawankar et al reported a case of stromal keratitis in dengue fever, in a 25-year-old female [ 15 ]. The patient developed stromal keratitis 15 days post dengue fever.…”

Section: Discussionmentioning

confidence: 99%

Ophthalmic manifestations as the first presenting feature in dengue fever: a 10-year study

2024

RJO

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“…1 2 3 27 40 41 Panophthalmitis and anterior segment manifestations including anterior uveitis and stromal keratitis are less common. 42 43 …”

Section: R Esultsmentioning

confidence: 99%

“…Other posterior segment involvements include optic neuritis, neuroretinitis, central retinal artery occlusion, and exudative retinal detachment. 41 42 48 58 59 Although ocular manifestations typically have a benign clinical course, optic neuritis may result in permanent visual loss. Recently, recurrence in Chikungunya retinitis has been reported.…”

Section: R Esultsmentioning

confidence: 99%

Ocular manifestations of emerging arthropod-borne infectious diseases

et al. 2021

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Purpose: To review the clinical features, diagnosis, treatment modalities, and prognosis of arthropod-borne infectious diseases. Methods: This is a narrative review on arthropod-borne infectious diseases including general and ophthalmological aspects of these infectious diseases. A comprehensive literature review between January 1983 and September 2020 was conducted in PubMed database. Epidemiology, clinical features, diagnosis, treatment, and prognosis of arthropod-borne infectious diseases were reviewed. Results: Emergent and resurgent arthropod-borne infectious diseases are major causes of systemic morbidity and death that are expanding worldwide. Among them, bacterial and viral agents including rickettsial disease, West Nile virus, Dengue fever, Chikungunya, Rift valley fever, and Zika virus have been associated with an array of ocular manifestations. These include anterior uveitis, retinitis, chorioretinitis, retinal vasculitis, and optic nerve involvement. Proper clinical diagnosis of any of these infectious diseases is primarily based on epidemiological data, history, systemic symptoms and signs, and the pattern of ocular involvement. The diagnosis is confirmed by laboratory tests. Ocular involvement usually has a self-limited course, but it can result in persistent visual impairment. Doxycycline is the treatment of choice for rickettsial disease. There is currently no proven specific treatment for arboviral diseases. Prevention remains the mainstay for arthropod vector and zoonotic disease control. Conclusions: Emerging arthropod vector-borne diseases should be considered in the differential diagnosis of uveitis, especially in patient living or with recent travel to endemic countries. Early clinical diagnosis, while laboratory testing is pending, is essential for proper management to prevent systemic and ocular morbidity.

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“…Finally, a medical disorder might concurrently occur after COVID-19 vaccination. For example, dengue is reported in vaccine recipient [ 3 ] and stromal keratitis is also a possible rare clinical problem induced by dengue [ 4 ].…”

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confidence: 99%