“…The patient's history should be carefully analyzed to rule out traumatic causes such as surgery, accidental traumas or selfinflicted lesions (nose picking) (42,86) . Infections such as tuberculosis, tertiary syphilis (76) , mucormycosis in immunocompromised patients (92) and septal abscesses should be considered when approaching midline destructive lesions (6) .…”
Section: Differential Diagnosismentioning
confidence: 99%
“…All chronic cocaine users seem to be similarly subject to the local ischaemic and irritating effects of cocaine crystals (88) . The consequent diffuse crusting and resultant traumatic removal of tightly adhering scabs, often performed with foreign bodies such as pens or pencils or even the articulating arm of an umbrella (42,74) , should affect all cocaine users similarly. Likewise, bacterial superinfections of damaged nasal mucosa should differently affect cocaine users based on their individual level of local mucosal damage (6) .…”
CIMDL must be readily recognized by clinicians to provide appropriate treatment. Immunosuppressive therapy has no role in the treatment of CIMDL. Only abstinence can interrupt the progression of the disease.
“…The patient's history should be carefully analyzed to rule out traumatic causes such as surgery, accidental traumas or selfinflicted lesions (nose picking) (42,86) . Infections such as tuberculosis, tertiary syphilis (76) , mucormycosis in immunocompromised patients (92) and septal abscesses should be considered when approaching midline destructive lesions (6) .…”
Section: Differential Diagnosismentioning
confidence: 99%
“…All chronic cocaine users seem to be similarly subject to the local ischaemic and irritating effects of cocaine crystals (88) . The consequent diffuse crusting and resultant traumatic removal of tightly adhering scabs, often performed with foreign bodies such as pens or pencils or even the articulating arm of an umbrella (42,74) , should affect all cocaine users similarly. Likewise, bacterial superinfections of damaged nasal mucosa should differently affect cocaine users based on their individual level of local mucosal damage (6) .…”
CIMDL must be readily recognized by clinicians to provide appropriate treatment. Immunosuppressive therapy has no role in the treatment of CIMDL. Only abstinence can interrupt the progression of the disease.
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