2017
DOI: 10.1155/2017/4303298
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An Unusual Mechanism of Closure of Muscular Ventricular Septal Defects

Abstract: Ventricular septal defects (VSDs) are the most common congenital heart defects. Most of the small or moderate size (<6 mm) muscular VSDs close spontaneously within the first two years of life. The usual mechanism of spontaneous closure involves muscular tissue encroachment with superimposed fibrosis or primary fibrous tissue formation around the margins of the defect. We describe an unusual mechanism of spontaneous closure of a muscular VSD.

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Cited by 3 publications
(3 citation statements)
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“…The authors presented transthoracic echocardiogram and cardiac Magnetic resonance imaging images of a case of midmuscular ventricular septal defect that closed spontaneously by growth of right ventricular trabeculations without obliteration of the defect. 6 Our case confirms that this rare mechanism of spontaneous closure of muscular ventricular septal defect does exist. We provide additional imaging by three-dimensional echocardiography.…”
Section: Discussionsupporting
confidence: 85%
“…The authors presented transthoracic echocardiogram and cardiac Magnetic resonance imaging images of a case of midmuscular ventricular septal defect that closed spontaneously by growth of right ventricular trabeculations without obliteration of the defect. 6 Our case confirms that this rare mechanism of spontaneous closure of muscular ventricular septal defect does exist. We provide additional imaging by three-dimensional echocardiography.…”
Section: Discussionsupporting
confidence: 85%
“…In the case, fibrotic tissue replaced the defect, but gross examination revealed a small depression on the interventricular septum’s left side [11]. Secondly, Dasgupta S [12] proposed another possible mechanism for closure of muscular VSD: right ventricular endocardial tissue proliferation and coverage. In the report, a 4 mm midmuscular VSD with a left-to-right shunt in a 2-month-old female infant was observed by echocardiography.…”
Section: Discussionmentioning
confidence: 99%
“…1, Additional file 1: Video S1). These structures were suspected to be coronary fistulas, dilated coronary vessels or unusual VSD tracts within the ventricular septum [4]. The infant subsequently developed a grade 4 intraventricular hemorrhage and passed away on the fourth day of life.…”
Section: Case Presentationmentioning
confidence: 99%