2012
DOI: 10.1136/bcr-2012-007648
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An unusual effect of interferential therapy

Abstract: SummaryIn this report, a patient with severe shoulder pain was treated with interferential currents, a commonly used modality in physiotherapy for the management of pain. He reported loss of concentration, drowsiness, decreased alertness and gait disturbance, along with analgaesia, for 4-5 h after each treatment. He was regularly taking tramadol HCl for pain relief. Endogenous opioids produced in response to interferential therapy may be excessive or may interact with the tramadol HCl and potentiate its effect… Show more

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Cited by 4 publications
(2 citation statements)
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“…Regarding the safety of the treatment, a Post Market Surveillance program to ensure the safety, quality, and performance has been conducted by the manufacturer since ANF started to be used in 2012, and several mild and short-term known side effects have been observed, specifically: headache, dry mouth, dizziness, light headedness, light flu-like symptoms, shivers, fatigue, general discomfort, runny nose, hives or skin issues, itching, nausea, vomiting, and diarrhea. A potential explanation for such symptoms is the overreaction or sensitivity of the body, which has been observed in similar frequency-based treatments 13) or the possibility that the treatment might potentiate medication effects and side effects by its effect on the endogenous opioid system 14) . This is the first study to scientifically assess and report on the effects of ANF, as well as its feasibility and satisfaction.…”
Section: Introductionmentioning
confidence: 99%
“…Regarding the safety of the treatment, a Post Market Surveillance program to ensure the safety, quality, and performance has been conducted by the manufacturer since ANF started to be used in 2012, and several mild and short-term known side effects have been observed, specifically: headache, dry mouth, dizziness, light headedness, light flu-like symptoms, shivers, fatigue, general discomfort, runny nose, hives or skin issues, itching, nausea, vomiting, and diarrhea. A potential explanation for such symptoms is the overreaction or sensitivity of the body, which has been observed in similar frequency-based treatments 13) or the possibility that the treatment might potentiate medication effects and side effects by its effect on the endogenous opioid system 14) . This is the first study to scientifically assess and report on the effects of ANF, as well as its feasibility and satisfaction.…”
Section: Introductionmentioning
confidence: 99%
“…26 This is supported by a case report of a patient taking concurrent tramadol who displayed the effects of opioid use such as drowsiness, decreased alertness and inability to concentrate for several hours after treatment by interferential current therapy. 27 It was hypothesized that interferential current therapy stimulated production of endorphins or enkephalins and that the additive effect of tramadol triggered this response. However, these theories have yet to be confirmed and indeed a placebo response has not been adequately excluded.…”
Section: Potential Actions Of Interferential Current Therapy On Variomentioning
confidence: 99%