Abstract:INTRODUCTION: Thrombotic Thrombocytopenia Purpura (TTP) is characterized by intravascular destruction of erythrocytes and blood platelets leading to microangiopathic hemolytic anemia, thrombocytopenia, renal failure, neurological changes, and fevers. TTP has an untreated mortality rate of > 90%. TTP-like disorders have been associated with medications, human immunodeficiency virus, bone marrow transplantation, and pregnancy, however, most cases are sporadic. There are multiple hypothesis regarding the pathogen… Show more
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