An unusual cause of anaemia

Findlay, Paul F; Sutherland, John M.

doi:10.1136/pgmj.74.876.617

Cited by 2 publications

(4 citation statements)

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“…Aspirin and other medicaments that impair hemostasis are contraindicated in such cases. (16) Our patient required the combination of blood transfusions and iron therapy in order to treat the gastrointestinal bleeding.…”

Section: Discussionmentioning

confidence: 98%

“…(6,(19)(20) In the previously mentioned 9 studies, the most common cause of severe anemia in patients with HHT was found to be chronic gastrointestinal bleeding (in 70%), followed by epistaxis (in 25%). (9)(10)(11)(12)(13)(14)(15)(16)(17) Recurrent gastrointestinal tract hemorrhage occurs in up to one-third of individuals with HHT. The risk of such hemorrhage increases with advancing age, typically appearing in the fifth or sixth decade of life.…”

Section: Discussionmentioning

confidence: 99%

“…(18) Although recurrent epistaxis becomes more severe with advancing age in approximately two-thirds of all individuals with HHT, (4) the disorder can also go undetected for many years and might be less common in adults. (16) Currently, there is no satisfactory treatment for HHT. Appropriate management depends on the clinical m anifestations and the site of the disease.…”

Section: Discussionmentioning

confidence: 99%

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Telangiectasia hemorrágica hereditária: uma causa rara de anemia grave

et al. 2007

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Hereditary hemorrhagic telangiectasia is an autosomal dominant disease in which arteriovenous communications are typically seen in the skin, mucosal surfaces, lungs, brain and gastrointestinal tract. This disease typically presents as epistaxis, gastrointestinal bleeding and arteriovenous malformations (in the brain and lungs). Although the epistaxis and gastrointestinal bleeding can result in anemia, patients diagnosed with hereditary hemorrhagic telangiectasia rarely present severe anemia. Herein, we report the case of a 49-year-old man with severe anemia and undiagnosed hereditary hemorrhagic telangiectasia. Keywords:Hereditary hemorrhagic telangiectasia; Iron deficiency anemia; Case reports [publication type]. ResumoTelangiectasia hemorrágica hereditária é uma doença autossômica dominante na qual comunicações arteriovenosas afetam comumente pele, superfícies mucosas, pulmões, cérebro e trato gastrointestinal. As manifestações comuns desta doença são epistaxe, sangramento gastrointestinal, e malformações arteriovenosas cerebrais e pulmonares. Apesar de a epistaxe e o sangramento gastrointestinal poderem causar anemia, telangiectasia hemorrágica hereditária raramente é diagnosticada com anemia grave. Neste artigo é relatado o caso de um homem de 49 anos de idade com telangiectasia hemorrágica hereditária não diagnosticada e anemia grave.

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Section: Discussionmentioning

confidence: 98%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Telangiectasia hemorrágica hereditária: uma causa rara de anemia grave

et al. 2007

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“…Sir, For the sake of completeness, among the neurological complications listed for haemorrhagic telangiectasia (HHT),1 due account should be taken, not only of cerebral abscess (which may be recurrent),2 but also of meningitis, which may also be recurrent,3 both complications being the sequelae of bypassing of the pulmonary filter by bacteria and septic microemboli, as a consequence of a right to left shunt 45 and this possibility makes HHT a potential risk factor for this kind of presentation, even in the elderly.…”

mentioning

confidence: 99%