Duodenal papillary adenoma is a rare benign gastrointestinal neoplasm with a reported incidence of 0.04%-0.12%. 1 However, it has a malignant potential and usually coexists with duodenal papillary carcinoma. 2 Moreover, duodenal papillary adenoma is insidious in terms of disease onset and is often asymptomatic in the early stage. As the disease progresses, non-specific symptoms such as fever, vomiting, abdominal pain, and jaundice may develop. 3 Although establishing an