An unprecedented strategy for selective and sensitive fluorescence detection of nitric oxide based on its reaction with a selenide

Sun, Chengdong; Shi, Wen; Song, Young-Chae; Chen, Wei; Ma, Huimin

doi:10.1039/c1cc12174j

Cited by 107 publications

(41 citation statements)

References 34 publications

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“…Sun et al 72 reported studies on the rhodamine-based fluorescence probe 38 for detecting NO (Scheme 6). The probe itself displays only weak fluorescence because it possesses a less conjugated spirocyclic selenolactone structure.…”

Section: Fluorescent Probes Containing Selenium For Other Significantmentioning

confidence: 99%

“…In addition, as mentioned above, 38 also acts as a NO probe. 72 Inspired by the antitoxic function of selenium toward heavy metal ions, Tang et al 82 designed the organoselenophosphate fluorescent probe 48 for Hg 2+ , which contains a fluorescein fluorophore (Scheme 8). The probe shows high sensitivity and selectivity toward Hg 2+ over other relevant metal ions and bioanalytes.…”

Section: Selenium-containing Fluorescent Probes For Cations and Anionsmentioning

confidence: 99%

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Fluorescent Probes Containing Selenium as a Guest or Host

Chen

Kwon

et al. 2016

Chem

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Selenium is an important trace element in living systems. Proteins incorporating selenium have a wide range of biological effects, ranging from anti-oxidant and antiinflammatory effects to the production of active thyroid hormones. In the past decades, selenium has drawn enormous attention because of its important role in biology, which can be ascribed partly if not solely to its redox and hard and soft donor properties. With the use of chemical mimicry, a large number of seleniumrelated fluorescent probes have been developed for monitoring physiological and pathological processes. This review, which summarizes recent progress made in this area, comprises two major sections. In the first section, fluorescent probes for selenium-containing species, such as selenocysteine (Sec), hydrogen selenide, thioredoxin reductases (TrxRs), and selenite, are described. This is followed by a discussion of fluorescent probes that contain selenium and detect reactive oxygen, nitrogen, and sulfur species, as well as cations and anions.

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Section: Fluorescent Probes Containing Selenium For Other Significantmentioning

confidence: 99%

Section: Selenium-containing Fluorescent Probes For Cations and Anionsmentioning

confidence: 99%

Fluorescent Probes Containing Selenium as a Guest or Host

Chen

Kwon

et al. 2016

Chem

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“…45 Moreover, RBSe is also an organic-based fluorescent probe that directly reacts with NO. Furthermore, rhodamine B is a more polar zwitterion and thus may be well-retained in cells.…”

Section: Fluorescent Sensors Based On Other Organic Functional Groupsmentioning

confidence: 99%

Fluorescent probes for real-time measurement of nitric oxide in living cells

Wan

2015

Analyst

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Nitric oxide (NO) is an important signaling molecule in biology. Both NO excess and insufficiency have been implicated in numerous physiological and pathological conditions. In order to study the diverse biological roles of NO in cells and tissues, many techniques have been developed for assaying NO. Recently, new generations of fluorescent probes have become indispensible tools for the study of NO biology because of their sensitivity, selectivity, spatiotemporal resolution, and experimental feasibility. Rational application of these probes in the study requires the understanding of the molecular mechanism that the probes are involved in. In this review, we will present an arsenal of fluorescent probes used to detect NO in living cells and animal tissues. We will also discuss the molecular mechanisms, actualities and prospects of fluorescent probes in detecting NO in cell biology.

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“…7 Sensitive and selective detection of short lived NO in vitro is a great challenge, which has been developed recently. [8][9][10] Fontijn et al applied gas phase chemiluminescence to detect NO based on the reaction of NO with ozone generating nitrogen dioxide in the excited state. 11 However, the method was not only expensive but also time consuming.…”

Section: Introductionmentioning

confidence: 99%

Bovine serum albumin template synthesis of fluorescent gold nanoclusters for nitric oxide detection in vitro

Zhao

Xuan

Wan

et al. 2016

Materials Technology

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Bovine serum albumin (BSA) stabilised gold nanoclusters (Au NCs) were prepared and used for nitric oxide (NO) detection in vitro. The prepared BSA-Au NCs with an average diameter of 1.5 nm emitted strong red photoluminescence (PL), accompanied with the maximum emission peak at 640 nm. Furthermore, the BSA-Au NCs were developed as a PL probe for NO detection in vitro.Owing to the damage of BSA-Au NCs structure caused by the interaction between NO and BSA, the PL intensity of BSA-Au NCs regularly reduced with the increase in NO concentration [NO]. There is a proportional relationship between the PL intensity of BSA-Au NCs and the [NO] (0.05-0.35 mM), together with a detection limit of 0.017 mM. Experimental results confirmed high selectivity and sensitivity of the NO probe over other reactive oxygen and nitrogen species, and presented excellent detection capacity in aqueous model samples.

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An unprecedented strategy for selective and sensitive fluorescence detection of nitric oxide based on its reaction with a selenide

Abstract: A new strategy that utilizes the interaction between NO and a selenide is reported for fluorescence detection of NO, in which rhodamine B selenolactone serves as a model selenide.

Cited by 107 publications

References 34 publications

Fluorescent Probes Containing Selenium as a Guest or Host

Fluorescent Probes Containing Selenium as a Guest or Host

Fluorescent probes for real-time measurement of nitric oxide in living cells

Bovine serum albumin template synthesis of fluorescent gold nanoclusters for nitric oxide detection in vitro

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