An unfortunate case of post-ERCP complications

Fiorini, Massimo; Pietrangelo, Antonello; Vegetti, Alberto

doi:10.1007/s11739-016-1474-y

Cited by 6 publications

(1 citation statement)

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“…In this study, there was no incidence of dysphagia in either control group or the benzydamine hydrochloride group while complaints of nausea and vomiting were comparable in both groups. However, the ERCP procedure itself can also precipitate nausea and vomiting due to contrast used during procedure or pancreatic inflammation, which is a serious complication of this procedure [15,16]. In addition, the use of fentanyl in ERCP anesthesia procedure may cause nausea and vomiting postprocedure [12].…”

Section: Discussionmentioning

confidence: 99%

Effectivity of benzydamine hydrochloride gargle to reduce propofol consumption in endoscopic retrograde cholangiopancreatography procedure: a randomized controlled trial

et al. 2020

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Background: Endoscopic Retrograde Cholangiopancreatography (ERCP) is a complex endoscopic procedure that requires moderate to deep sedation. Propofol is the sedative agent of choice for sedation in ERCP due to its fast distribution and fast elimination time without a cumulative effect after infusion, resulting in shorter recovery time. Benzydamine hydrochloride is a topical non-steroidal anti-inflammatory drug that has analgesic, local anesthetic, and anti-inflammatory effects that have been known to be effective in reducing postoperative sore throat. Combination of propofol and topical analgesic may provide adequate sedation and reduce propofol consumption. This study aimed to determine the effectivity of benzydamine hydrochloride gargling in reducing propofol consumption in the ERCP procedure. Methods: This study was a single-blind randomized controlled trial for patients undergoing ERCP procedures at Cipto Mangunkusumo Hospital from August to September 2018. A total of 72 subjects were recruited consecutively and randomly assigned into two groups. The first group received 15 mL of 0.15% benzydamine hydrochloride mouthwash prior to the procedure, whereas the second group received 15 mL of water mouthwash. Additional propofol was administered when patient moved or Ramsay Sedation Scale rose above 4. Cumulative propofol consumption per kg body weight per minute and incidence of postoperative sore throat were recorded in each group. Incidence of desaturation, postoperative nausea vomitting, and dysphagia were also recorded. Data analysis was performed with Statistical Package for the Social Sciences.

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Section: Discussionmentioning

confidence: 99%