An Uncommon Presentation of Brain Metastases in a Lung Cancer Patient

Freiburg Neuropathology Case Conference

“…They may be of variable density on NCCT and often show surrounding edema that is disproportional to the tumor size [ 21 ]. On MRI they are usually isointense to hypointense on T1, hyperintense on T2/FLAIR and may show intense, punctate, nodular or ring enhancement depending on their size [ 21 ]; however, case reports have shown that brain metastasis can also lead to enhancement along perivascular spaces [ 22 ] as seen in this case. Thus, it is wise to consider metastasis as a potential differential diagnosis in all patients with an intra-axial mass lesion, regardless of the enhancement pattern.…”