An uncommon association: Chicken pox and Guillain–Barre syndrome

Çokyaman, Turgay; Karli, Arzu; Tekin, Emine; Şensoy, Gülnar; Taşdemir, Haydar Ali

doi:10.1016/j.jiph.2014.09.006

Cited by 5 publications

(5 citation statements)

References 5 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…[ 101 ] Another case study reported a rare but severe neurological complication of chickenpox, Guillain–Barre syndrome, in a 4-year-old child. [ 102 ] In addition, a rare case was reported of primary inoculation tuberculosis seen after varicella. [ 103 ] The case explained the possible mechanism of VZV-mediated transient cellular immune suppression that predisposed the patient to cutaneous tuberculosis.…”

Section: Turkeymentioning

confidence: 99%

Varicella infection in the Middle East: Prevalence, complications, and vaccination

Al-Turab

Chehadeh

2018

J Res Med Sci

View full text Add to dashboard Cite

Varicella (chickenpox) is the primary infection of varicella-zoster virus (VZV), it is a mild self-limiting infection, but it is also highly contagious and can cause severe complications among high-risk group of individuals. It is usually a childhood infection providing lifelong immunity, but adults without varicella history are also susceptible to infection. High-risk group of individuals is more likely to develop serious complications. Varicella vaccine was introduced to protect this group of individuals and to prevent epidemic spread of VZV infection in a community. Thus, it was added to the recommended vaccination schedules for children in most developed countries. This review aimed to outline varicella status, seroprevalence, complications, and vaccination in the Middle East region. Based on our findings, children were the most affected age group, but there are also adult cases due to high number of expatriates, especially in Gulf Cooperation Council countries. Central nervous system involvements and skin diseases followed by varicella pneumonia were the most varicella-associated complications. Varicella vaccine was introduced in most Middle East countries, either mandatory by the Ministries of Health or optional in the private clinics. Few numbers of studies have reported an obvious reduction in varicella prevalence, hospitalizations, and deaths in the Middle East following varicella vaccination. A basic database about varicella infection before the initiation and implementation of a vaccination policy is essential to determine the target group of individuals. As far as our knowledge, this is the first review about varicella infection in the Middle East.

show abstract

Section: Turkeymentioning

confidence: 99%

Varicella infection in the Middle East: Prevalence, complications, and vaccination

Al-Turab

Chehadeh

2018

J Res Med Sci

View full text Add to dashboard Cite

show abstract

“…The treatment is based, in addition to the measures of resuscitation and local care on Aciclovir at 10 mg/kg/ 08h for one Minimum of seven days [1,2,4]. The delay in management anticipates mortality and functional sequelae [3]. What was the case with this patient Consulted belatedly.…”

Section: Discussionmentioning

confidence: 92%

“…Guillain-Barre syndrome (GBS) is a rare but severe neurological complication of chickenpox that can cause sequela [3]. The mechanism of Schwann cellular attack after VZV infection is poor but this case suggests that primary VZV infection may Stimulus sufficient to drive antibody generation and precipitate severe clinical symptomatology [4,5].…”

Section: Discussionmentioning

confidence: 99%

Guillain-Barré Syndrome Following a Malignant Varicella in Immunocompetent Adult

Elmahi¹,

Baybay²,

Issoual³

et al. 2017

IJCDR

View full text Add to dashboard Cite

“…Of the 24 reported patients [13][14][15][16][17][18][19][20][21][22][23][24][25][26][27][28][29][30][31][32] who developed GBS after chicken pox (Table 1), 17 (71%) were male (age range, 2 to 53 years old). Duration between skin rash and developing weakness ranged from 4 to 21 days.…”

Section: Gbs Following Chicken Pox or Varicellamentioning

confidence: 99%

Guillain-Barré syndrome following varicella-zoster virus infection

Islam

GeurtsvanKessel

et al. 2018

Eur J Clin Microbiol Infect Dis

View full text Add to dashboard Cite

We describe the frequency, clinical features, and electrophysiological and immunological phenotypes of Guillain-Barré Syndrome (GBS) patients treated at a single institution in Bangladesh who had preceding chicken pox (primary Varicella-zoster virus [VZV] infection) within 4 weeks of GBS onset. A literature review of GBS cases preceding VZV infection is also provided. Diagnosis of GBS was based on the National Institute of Neurological Disorders and Stroke criteria for GBS. Serum anti-VZV IgM and IgG antibodies were quantified by indirect chemiluminescence immunoassay (CLIA); anti-Campylobacter jejuni IgG, IgM, and IgA antibodies and anti-ganglioside GM1 IgM and IgG antibodies, by enzyme-linked immunosorbent assays. Neurophysiologic subtypes were categorized following the Hadden criteria. Of 536 patients with GBS, 7 (1.3%) had chicken pox within 4 weeks before GBS onset. Four of the seven cases were male (age range, 23 to 40 years old). All seven patients were bed-bound, six had sensory symptoms, and three required mechanical ventilation for respiratory failure. All seven patients had CSF albuminocytologic dissociation and evidence of demyelination in nerve conduction studies. Anti-VZV IgM antibodies were present and anti-GM1 and anti-Campylobacter jejuni lipo-oligosaccharides (LOS) were negative in all cases. All patients had excellent outcome at 1 year (able to run). A systematic literature review of GBS cases related to VZV revealed 39 previously reported patients with comparable clinical presentations and outcomes, of which 36 had neurophysiologic evidence of demyelination. VZV infection is associated with the demyelinating subtype of GBS, clearly distinct from the axonal form of GBS that predominate in countries like Bangladesh.

show abstract

An uncommon association: Chicken pox and Guillain–Barre syndrome

Cited by 5 publications

References 5 publications

Varicella infection in the Middle East: Prevalence, complications, and vaccination

Varicella infection in the Middle East: Prevalence, complications, and vaccination

Guillain-Barré Syndrome Following a Malignant Varicella in Immunocompetent Adult

Guillain-Barré syndrome following varicella-zoster virus infection

Contact Info

Product

Resources

About