An ultrasensitive non-enzymatic amperometric glucose sensor based on a Cu-coated nanoporous gold film involving co-mediating

Guo, Manman; Wang, Pengshu; Zhou, Chaohui; Xia, Yue; Huang, Wei; Li, Zelin

doi:10.1016/j.snb.2014.07.007

Cited by 63 publications

(32 citation statements)

References 76 publications

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“…In a broad potential range from −0.9 V to 0.6 V, Au(I) and Au(III) incipient hydrous oxide species with different oxidative abilities reacted with glucose, resulting in different peak currents. 33 Similar behaviors were also observed on the bare gold electrode. Fig.…”

Section: Resultssupporting

confidence: 67%

A Rapid Anodic Fabrication of Nanoporous Gold in NH₄Cl Solution for Nonenzymatic Glucose Detection

Zhou

Xia

Huang

et al. 2014

J. Electrochem. Soc.

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One-step anodic potential step treatment of pure gold electrode in HCl or KCl solution is a simple and efficient strategy to form nanoporous structures. This method has now been employed in NH 4 Cl solution to fast construct nanoporous gold (NPG) electrode for nonenzymatic glucose detection. The surface area of as-prepared NPG was greatly increased by adding the proper amount of NH 2 OH · HCl as anodic depolarizer and reducing agent, resulting in the improved sensitivity for glucose determination. In situ Raman spectroscopy confirmed the existence of gold oxides, which is vital for the formation of NPG during anodization in Cl − -containing electrolyte. The electrocatalytic oxidation of glucose on the NPG and the corresponding amperometric detection of glucose was investigated. Comparing with our prior published one (Biosens. Bioelectron., 2011, 26, 3555-3561), NPG reported here exhibited increased sensitivity and wider linear range for glucose detection in phosphate buffered saline (PBS) solution in the presence of Cl − ; a broad linear relationship from 0.2 to 16 mM (corresponding to 0.036 to 2.7 g L −1 ) at −0.4 V and a high sensitivity of 3625 μA mM −1 cm −2 at 0.2 V was achieved in 0.1 M NaOH. The good selectivity and reproducibility make NPG a promising nonenzymatic glucose sensing platform.Glucose monitoring is very important for the people who are suffering from diabetes. Commercially available glucose sensors based on immobilized enzyme have been extensively employed for the past three decades. 1-4 Though enzymatic detection exhibits excellent selectivity and good sensitivity, the bioactivity of enzyme can be easily affected by the immobilization method and temperature, humidity, pH, toxic chemicals, etc. Therefore, simple nonenzymatic glucose sensitive electrodes attracted increasing attention due to their low cost, good thermal and chemical stability. Various nanomaterials including noble metals, alloys and metal oxides that are capable of directly electrooxidizing glucose have been explored for fabricating enzyme-free glucose sensors. [5][6][7] Nanoporous gold (NPG) as an electrode material is attractive in electrocatalysis and electroanalytical chemistry due to its large surface area, good biocompatibility and high electrocatalytic activity. 8-10 Methods used to fabricate NPG structures can mainly be classified into dealloying, template-directed multistep synthesis and electrochemical preparation. Dealloying Au-Ag 11 or Au-Zn 12 alloy has been widely used and investigated. In such cases, alloy with specific composition should be prepared in advance. Furthermore, the procedure of dealloying is time-consuming and the prepared NPG films are hard to handle and reuse when used as an electrode substrate. Template-directed synthesis of NPG is usually multistep and tedious since additional operations to build and remove templates are required. 13,14 Electrochemical method is a relative simple and green alternative route to fabricate NPG, which avoids the possible contaminations induced by impurities in deall...

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Section: Resultssupporting

confidence: 67%

A Rapid Anodic Fabrication of Nanoporous Gold in NH₄Cl Solution for Nonenzymatic Glucose Detection

Zhou

Xia

Huang

et al. 2014

J. Electrochem. Soc.

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“…So far, many micro/nanomaterials have been fabricated to construct nonenzymatic glucose sensors such as carbons, noble metals (Au, Ag, Pd and Pt), cheaper metals (Cu, Ni, Fe, Co, and Mn) as well as their oxides and sulfides [15][16][17][18][19][20][21][22], and Cu-, Ni-or CoO-coated nanoporous Au [23][24][25].…”

Section: Introductionmentioning

confidence: 99%

“…CuO nanowires [26], CuO nanospheres [27], CuO nanoflowers [28], CuS nanotubes [21], Cu foams [29], and Cu-coated nanoporous Au [23] are representative examples that were used in nonenzymatic glucose sensing. Notably, porous structures are beneficial due to their enlarged surface area for reactions and charge transport, plentiful channels for mass transport, and the structural effects such as discriminative electrokinetics, nano-confinement, electrical double layer overlapping, ion-selective impedance, etc [30][31][32].…”

Section: Introductionmentioning

confidence: 99%

Electrochemical fabrication of stalactite-like copper micropillar arrays via surface rebuilding for ultrasensitive nonenzymatic sensing of glucose

Guo

Xia

Huang

et al. 2015

Electrochimica Acta

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“…Moreover, the NPG films possess a better structural stability than the other Au-based catalysts with porous, single or polycrystalline structure during long-time CV tests due to the fewer residual Ag content [15,16,28]. Compared with the other synthesis routes [25,26] and decorated strategies [2,27,29], NPG film prepared by pulse electrochemical dealloying is relatively controllable, easy operable and high-performing.…”

Section: Electrocatalytic Stabilitymentioning

confidence: 99%

Effects of pore size and residual Ag on electrocatalytic properties of nanoporous gold films prepared by pulse electrochemical dealloying

Chen

Wang

et al. 2015

Electrochimica Acta

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An ultrasensitive non-enzymatic amperometric glucose sensor based on a Cu-coated nanoporous gold film involving co-mediating

Cited by 63 publications

References 76 publications

A Rapid Anodic Fabrication of Nanoporous Gold in NH₄Cl Solution for Nonenzymatic Glucose Detection

A Rapid Anodic Fabrication of Nanoporous Gold in NH₄Cl Solution for Nonenzymatic Glucose Detection

Electrochemical fabrication of stalactite-like copper micropillar arrays via surface rebuilding for ultrasensitive nonenzymatic sensing of glucose

Effects of pore size and residual Ag on electrocatalytic properties of nanoporous gold films prepared by pulse electrochemical dealloying

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An ultrasensitive non-enzymatic amperometric glucose sensor based on a Cu-coated nanoporous gold film involving co-mediating

Cited by 63 publications

References 76 publications

A Rapid Anodic Fabrication of Nanoporous Gold in NH4Cl Solution for Nonenzymatic Glucose Detection

A Rapid Anodic Fabrication of Nanoporous Gold in NH4Cl Solution for Nonenzymatic Glucose Detection

Electrochemical fabrication of stalactite-like copper micropillar arrays via surface rebuilding for ultrasensitive nonenzymatic sensing of glucose

Effects of pore size and residual Ag on electrocatalytic properties of nanoporous gold films prepared by pulse electrochemical dealloying

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A Rapid Anodic Fabrication of Nanoporous Gold in NH₄Cl Solution for Nonenzymatic Glucose Detection

A Rapid Anodic Fabrication of Nanoporous Gold in NH₄Cl Solution for Nonenzymatic Glucose Detection