An ultra-sensitive kaempferol electrochemical sensor based on flower-like ZIF-8 pyrolysis-derived ZnWO4/porous nanocarbon composites

Wang, Yilin; Wang, Chenxi; Zhang, Li; Li, Jiaodi; Li, Rongjie; Fu, Qian; Li, Chunyan; Zhao, Pengcheng; Fei, Junjie

doi:10.1016/j.microc.2022.107519

Cited by 7 publications

(1 citation statement)

References 42 publications

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“…[28] Significantly, ZIF-8 has a good structure, water stability, and more active sites rather than other ZIFs. [29] Nevertheless, the weak surface hydrophilicity and lower conductivity have delayed the extensive applications of ZIF-8 in the electrochemical sensors. [30] Conversely, ZIF-8-derived materials afford more active sites and can improve the fast electron transfer rate in electrochemical sensors.…”

Section: Introductionmentioning

confidence: 99%

A Sandwich‐Type Electrochemical Immunosensor for Insulin Detection Based on Au‐Adhered Cu₅Zn₈ Hollow Porous Carbon Nanocubes and AuNP Deposited Nitrogen‐Doped Holey Graphene

Sakthivel

Prasanna

Tseng

et al. 2022

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Rapid, accurate, and sensitive insulin detection is crucial for managing and treating diabetes. A simple sandwich‐type electrochemical immunosensor is engineered using gold nanoparticle (AuNP)‐adhered metal–organic framework‐derived copper–zinc hollow porous carbon nanocubes (Au@Cu5Zn8/HPCNC) and AuNP‐deposited nitrogen‐doped holey graphene (NHG) are used as a dual functional label and sensing platform. The results show that identical morphology and size of Au@Cu5Zn8/HPCNC enhance the electrocatalytic active sites, conductivity, and surface area to immobilize the detection antibodies (Ab2). In addition, AuNP/NHG has the requisite biocompatibility and electrical conductivity, which facilitates electron transport and increases the surface area of the capture antibody (Ab1). Significantly, Cu5Zn8/HPCNC exhibits necessary catalytic activity and sensitivity for the electrochemical reduction of H2O2 using (i–t) amperometry and improves the electrochemical response in differential pulse voltammetry. Under optimal conditions, the immunosensor for insulin demonstrates a wide linear range with a low detection limit and viable specificity, stability, and reproducibility. The platform's practicality is evaluated by detecting insulin in human serum samples. All these characteristics indicate that the Cu5Zn8/HPCNC‐based biosensing strategy may be used for the point‐of‐care assay of diverse biomarkers.

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Section: Introductionmentioning

confidence: 99%

A Sandwich‐Type Electrochemical Immunosensor for Insulin Detection Based on Au‐Adhered Cu₅Zn₈ Hollow Porous Carbon Nanocubes and AuNP Deposited Nitrogen‐Doped Holey Graphene

Sakthivel

Prasanna

Tseng

et al. 2022

Small

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Green and Low-temperature Synthesis of Carbon Dots for Simple Detection of Kaempferol

Zeng

Peng

et al. 2023

J Fluoresc

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A Dual Emission Fluorescence Probe Based on Silicon Nanoparticles and Rhodamine B for Ratiometric Detection of Kaempferol

Pan,

Lu,

et al. 2024

J Fluoresc

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An ultra-sensitive kaempferol electrochemical sensor based on flower-like ZIF-8 pyrolysis-derived ZnWO4/porous nanocarbon composites

Cited by 7 publications

References 42 publications

A Sandwich‐Type Electrochemical Immunosensor for Insulin Detection Based on Au‐Adhered Cu₅Zn₈ Hollow Porous Carbon Nanocubes and AuNP Deposited Nitrogen‐Doped Holey Graphene

A Sandwich‐Type Electrochemical Immunosensor for Insulin Detection Based on Au‐Adhered Cu₅Zn₈ Hollow Porous Carbon Nanocubes and AuNP Deposited Nitrogen‐Doped Holey Graphene

Green and Low-temperature Synthesis of Carbon Dots for Simple Detection of Kaempferol

A Dual Emission Fluorescence Probe Based on Silicon Nanoparticles and Rhodamine B for Ratiometric Detection of Kaempferol

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An ultra-sensitive kaempferol electrochemical sensor based on flower-like ZIF-8 pyrolysis-derived ZnWO4/porous nanocarbon composites

Cited by 7 publications

References 42 publications

A Sandwich‐Type Electrochemical Immunosensor for Insulin Detection Based on Au‐Adhered Cu5Zn8 Hollow Porous Carbon Nanocubes and AuNP Deposited Nitrogen‐Doped Holey Graphene

A Sandwich‐Type Electrochemical Immunosensor for Insulin Detection Based on Au‐Adhered Cu5Zn8 Hollow Porous Carbon Nanocubes and AuNP Deposited Nitrogen‐Doped Holey Graphene

Green and Low-temperature Synthesis of Carbon Dots for Simple Detection of Kaempferol

A Dual Emission Fluorescence Probe Based on Silicon Nanoparticles and Rhodamine B for Ratiometric Detection of Kaempferol

Contact Info

Product

Resources

About

A Sandwich‐Type Electrochemical Immunosensor for Insulin Detection Based on Au‐Adhered Cu₅Zn₈ Hollow Porous Carbon Nanocubes and AuNP Deposited Nitrogen‐Doped Holey Graphene

A Sandwich‐Type Electrochemical Immunosensor for Insulin Detection Based on Au‐Adhered Cu₅Zn₈ Hollow Porous Carbon Nanocubes and AuNP Deposited Nitrogen‐Doped Holey Graphene