An SiO₂/ZnBr₂mediated expeditious approach to 3-methyl-1-phenyl-1H-pyrazol-5(4H)-one derivatives in water under microwave irradiation

Abstract

An efficient and eco-friendly synthesis of pyrazolone derivatives.

Silica Bonded N-(Propylcarbamoyl)sulfamic acid (SBPCSA) Mediated Expeditious Approach to C–C Bond Formation: An Innovative Pathway for Acrylonitrile Derivatives

“…In this regard, substantial research efforts have been devoted to develop catalysts with high efficacy, selectivity and stability. Immobilization of catalysts on solid support, leads to clean chemical synthesis for environmental as well as economical point of view [4,5]. Heterogeneous catalysts have gained much attraction of Electronic supplementary material The online version of this article (doi:10.1007/s10562-016-1793-7) contains supplementary material, which is available to authorized users.…”

Microwave‐Assisted One‐Pot Synthesis of New α‐Aminophosphonates Using ZnBr2‐SiO2 as a Catalyst under Solvent‐Free Conditions and Their Anticancer Activity

“…Some of the synthetic strategies have been accounted for the synthesis of α ‐aminophosphonates involving the reaction of amines, aldehydes with diethyl phosphite using various catalysts including SnCl 4 , SnCl 2 , ZnCl 2 , InCl 3 , AlCl 3 , CF 3 CO 2 H and TiO 2 . ZnBr 2 ‐SiO 2 catalyst is very much perceived as a precious procedure in organic synthesis in recent years and widely used for the synthesis of analgesic, anti‐tubercular, anti‐microbial, anti‐inflammatory, antioxidant, anti‐tumor reagent and other applications. The advantages of this catalyst for synthesizing α ‐aminophosphonates are enhanced reaction rate, selectivity, and low energy requirement.…”

“…The use of MW radiation offers new options in terms of sample preparation regarding shorter reaction time for synthesis and reduced solvent utilization . In this study, the usefulness of MW conditions to enhance the reaction subsequently increasing the yield compared with conventional conditions for the formation of the product has been studied.…”

“…In this study, the usefulness of MW conditions to enhance the reaction subsequently increasing the yield compared with conventional conditions for the formation of the product has been studied. The reaction was enormously enhanced by adding a little amount of ZnBr 2 ‐SiO 2 as a catalyst under MW irradiation conditions. Inventing selective, efficient and eco‐friendly techniques for applications in complex organic synthetic changes constitutes a noteworthy area of research in chemistry.…”

Chemistry of 2-amino-4-oxo-4H-1-benzopyran-3-carboxaldehydes

“…70 In this one-pot three-component reaction the phenylhydrazine at first forms with ethyl acetoacetate the pyrazolidinone 166 that condenses with 1 giving 167.…”