An Overview On Melatonin Hormone

Özçeli̇k, Fatih; Erdem, Murat; Bolu, Abdullah; Glsn, Murat

doi:10.5455/cap.20130512

Cited by 7 publications

(2 citation statements)

References 102 publications

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“…It should be remembered that there may be errors in the regulation of treatments, as well as an increased risk of self-injury in healthcare workers. It can be argued that the risk of injury to patients or healthcare workers will be higher for the night-shift group in our study, given the longer duration of the night-shift in our study (16 hours) compared to the duration of the night-shift (12 hours) in the study by Thompson et al 14 The imbalance of melatonin levels are known to be involved in the etiology of depression 15,16 . A study of hormonal changes reported a decrease in melatonin levels and an increase in inflammatory markers in nightshift workers 17,18 .…”

Section: Discussionmentioning

confidence: 55%

Effect of Shift Work in Intensive Care on Attention Disorder in Nurses

nmezdil

Ara

2020

Preprint

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Aim: The purpose of this study is to determine the level of attention between shifts and to make recommendations about the regulation of shifts. Methods:The researchers applied the Hamilton Depression Rating Scale (HAM-D), Hamilton Anxiety Rating Scale (HAM-A), Pittsburgh Sleep Quality Index (PSQI) and Stroop color word interaction test (SCWI) in 72 intensive care workers working in different shifts. Result: The study included a total of 72 participants, including 30 (43.3%) females and 42 (58.3%) males. There were statistically significant differences between the groups in the sub-items of the HAM-D and SCWI test (Table 3). There was a significant elongation in the night shift employees at all times within the SCWI sub-items. A significant height in the number of errors and corrections in the cards applied in the continuation of the test was also determined in the night shift group. Conclusion: This study revealed a significant decrease in the level of attention in the night-shift compared to the day-shift. This increase in attention deficit may also be a preventable cause of increased mortality in the night-shift What is already known about this topic? * Mortality rates in intensive care units are higher than in other clinics. What this paper adds? * Our study reported significantly poor results of the SCWI test in the night-shift compared to the day-shift. The implications of this paper: * This study revealed a significant decrease in the level of attention in the night-shift compared to the day-shift. We believe that it will be beneficial to shorten the shift times, to keep the number of patients per staff at international standards, to set active rest periods and to plan personnel and hours to reduce the lack of attention observed in the night shift. KEYWORDS Attention, healthcare worker, night-shift, intensive care Summary statement What is already known about this topic? Mortality rates in intensive care units are higher than in other clinics.

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Section: Discussionmentioning

confidence: 55%

Effect of Shift Work in Intensive Care on Attention Disorder in Nurses

nmezdil

Ara

2020

Preprint

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“…Melatonin is a neuroendocrine hormone that affects the growth, and reproduction of mammals ( 73 , 74 ). During the night (especially between 11:00 p.m. and 5:00 a.m.), blood melatonin levels increase 3-10 times and the secretion of melatonin peaks ( 75 ). Mice lacking melatonin receptors (such as MT1) had slightly higher daytime activity than mice without melatonin receptors deficiency ( 76 , 77 ), which suggests that melatonin may influence activity rhythms by acting on receptors.…”

Section: Discussionmentioning

confidence: 99%

Behavior and physiology in female Cricetulus barabensis are associated with the expression of circadian genes

Zhu,

Wu,

Mou

et al. 2024

Front. Endocrinol.

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The circadian clock regulates the behavior, physiology, and metabolism of mammals, and these characteristics, such as sleep-wake cycles, exercise capacity, and hormone levels, exhibit circadian rhythms. Light signaling is the main stimulator of the mammalian circadian system. The photoperiod regulates the reproductive cycle of seasonal breeding animals, and the circadian clock plays a pivotal role in this process. However, the role of the clock in coordinating animal behavior and physiology in response to photoperiodic changes needs further investigation. The present study investigated the changes and correlation of behavioral activities, physiological indicators, and gene expression in female striped hamsters (Cricetulus barabensis) within 24 h under a 12L:12D photoperiod. We found that the daily rhythms of sleep-wake and open field were significant in hamsters. The expression of clock genes, melatonin receptor genes, and genes involved in general metabolism oscillated significantly in central and peripheral tissues (brain, hypothalamus, liver, ovary, and thymus) and was significantly associated with behavior and physiology. Our results revealed that the neuroendocrine system regulated the rhythmicity of behavior and physiology, and central and peripheral clock genes (Bmal1, Clock, Per1, Per2, Cry1, and Cry2), melatonin receptor genes (MT1, MT2, and GPR50), and metabolizing genes (SIRT1, FGF21, and PPARα) played important roles. Our results suggest that central and peripheral circadian clocks, melatonin receptors, and genes involved in general metabolism may play key roles in maintaining circadian behavior and metabolic homeostasis in striped hamsters. Our results may have important implication for rodent pest control.

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Determination of Melatonin Differences between Day and Night Milk in Dairy Cattle

Şahin¹,

Akyürek²,

Aytekin³

et al. 2021

Tarım Bilimleri Dergisi

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The aim of this study was to determine the difference between melatonin hormone in night milk and melatonin concentration in day milk of Holstein cows. In this study, daytime milk obtained from 40 heads Holstein cows in the first lactation raised in a private dairy cattle farm in Karapınar district of Konya state province in Turkey and night milk samples taken from the same cows that were kept in darkness for one week were used. The milk samples were collected from day and night milking in order to determine the melatonin concentration with the help of Bovine Melatonin (MLT) Elisa Kit. In this study, melatonin concentration in day time and night time milk were determined as respectively 103.70 ± 6.61 pg mL -1 and 163.13 ± 8.96 pg mL -1 . The difference between melatonin levels of day and night milk was statistically significant (P<0.01). Since significant difference occurred between melatonin concentration between day and night milk at the end of the study, it can be stated that night milk can be used for medical purposes that is used cure of some illnesses and producers can be provided with a new production source.

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An Overview On Melatonin Hormone

Cited by 7 publications

References 102 publications

Effect of Shift Work in Intensive Care on Attention Disorder in Nurses

Effect of Shift Work in Intensive Care on Attention Disorder in Nurses

Behavior and physiology in female Cricetulus barabensis are associated with the expression of circadian genes

Determination of Melatonin Differences between Day and Night Milk in Dairy Cattle

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