An overview of treatment options for mild‐to‐moderate acne based on American Academy of Dermatology, European Academy of Dermatology and Venereology, and Italian Society of Dermatology and Venereology guidelines

Conforti, Claudio; Chello, Camilla; Giuffrida, Roberta; Meo, Nicola di; Zalaudek, Iris; Dianzani, Caterina

doi:10.1111/dth.13548

Cited by 23 publications

(48 citation statements)

References 30 publications

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“…Only 15% of the AV patients were reported to be able to reach dermatologists for treatment in the United States. 8 In contrary, in our study, we have found that the dermatologists were examining more AV patients than FPs. In our country, patients may directly admit to the dermatologists, and there is no obligation to apply to the primary care physicians beforehand.…”

Section: Discussioncontrasting

confidence: 81%

“…[4][5][6] Topical antibiotics may be preferred for mild papulopustular acne, whereas the systemic antibiotics are indicated for moderate/severe AV. 7,8 Dermatologists' preferences of antibiotics were in parallel with the guidelines in our study. throughout the world.…”

Section: Discussionmentioning

confidence: 81%

“…19,21,27,28 To prevent antibiotic resistance it is recommended to combine antibiotics with BP or retinoids. 8,31 These combinations may also provide more effective treatment for AV. 8 In our study, dermatologists T A B L E 4 Distribution of physicians who approves of the measures to be taken in order not to give rise to the development of antibiotic resistance .000…”

Section: Discussionmentioning

confidence: 99%

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Comparison of dermatologists and family physicians in terms of prescribing antibiotics for the treatment of acne vulgaris

Kayıran

Karadağ

Mutlu

et al. 2020

Dermatologic Therapy

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Acne vulgaris (AV) is a common skin disease that is treated both with dermatologists and family physicians (FPs) with different strategies. To assess the antibiotics that are frequently preferred in AV treatment, and the differences between the FPs and dermatologists in treatment were investigated. The physicians were informed about the study, and sent over the internet a multiple-choice questionnaire that consists of 29 questions in total. Afterwards, the answers provided were compared. 201 dermatologists and 147 FPs participated in the study. Dermatologists were found to have preferred topical erythromycin, nadifloxacin, clindamycin, and tetracycline, and systematically doxycycline and azithromycin in adult patients, whereas the FPs were found to have preferred mupirocin, fusidic acid (FA), and oxytetracycline, and systematically tetracycline. Dermatologists were found to have recommended topical clindamycin and erythromycin in pregnant/breastfeeding AV patients, whereas the FPs were found to have recommended FA. Dermatologists were found to have continued the antibiotics for 8 to 12 weeks, whereas the FPs were found to have continued for 1 to 4 weeks. The dermatologists preferred systemic antibiotics in cases with back involvement, moderate to severe AV, and that the FPs preferred them in severe AV. The dermatologists considered that the use of antibiotics alone or long-term were important factors causing antibiotic resistance. There were significant differences between the approaches of dermatologists and FPs to AV treatment. FPs were found to have insufficient information about prevention of antibiotic resistance. Therefore, we think that the continuous training of FPs on dermatology will be beneficial.

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Section: Discussioncontrasting

confidence: 81%

Section: Discussionmentioning

confidence: 81%

Section: Discussionmentioning

confidence: 99%

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Comparison of dermatologists and family physicians in terms of prescribing antibiotics for the treatment of acne vulgaris

Kayıran

Karadağ

Mutlu

et al. 2020

Dermatologic Therapy

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“…International guidelines recommend the use of topical antimicrobials mainly in the treatment of mild and moderate acne, including comedonal and localized papulopustular manifestations. 19,[21][22][23] However, their use as monotherapy is highly discouraged, as it is related to an extremely elevated risk for bacterial resistances. 21,22 Bacterial…”

Section: Topical Antibiotics For the Treatment Of Acne Vulgarismentioning

confidence: 99%

“…Therefore, the most recommended topical combinations currently include different concentrations of benzoyl peroxide associated with clindamycin or erythromycin, as well as fixed 0.025% tretinoin and 1.2% clindamycin gel formulations 21,22. All the major International guidelines strongly recommend the use of benzoyl peroxide together with topical antimicrobials (clindamycin or erythromycin) in most comedonal acne cases, leaving associations of both tretinoin and clindamycin to moderate papulopustular manifestations, with or without concomitant systemic antibiotic therapy 19,[21][22][23]. As for severe acne manifestations, in the end, topical therapies, including antimicrobial medications, are generally discour-…”

mentioning

confidence: 99%

Topical antibiotics in the dermatological clinical practice: Indications, efficacy, and adverse effects

Bonamonte

Marco

Giuffrida

et al. 2020

Dermatologic Therapy

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Topical antibiotic therapy is a central component of patient management for several skin conditions, including acne, hidradenitis suppurativa, rosacea, impetigo or other superinfected dermatitis, and prevention of wound infections. Moreover, particular situations, such as skin diseases of bacterial origin in pregnancy and infants often warrant topical therapy. However, the occurrence of local delayed hypersensitivity reactions and the rising rate of antibiotic resistance are becoming great challenges faced by many dermatologists today. This narrative review provides an overview of the main topical antibiotics used in dermatology, focusing on their clinical role in the most common dermatological indications. For this purpose, a review of MEDLINE and PubMed for pertinent, scientific, and clinical publications until March 2020 was performed. Only articles published in the English language were included.

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The Use of Lasers and Light Devices in Acne Management: An Update

Liu

Hsu

2021

Am J Clin Dermatol

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Acne vulgaris is a disease of the pilosebaceous unit and the most common inflammatory dermatosis worldwide. It is also associated with significant economic burden. Limitations of conventional topical and systemic treatments include long treatment course, intolerable adverse effects, antibiotic resistance, and patient compliance. Therefore, laser and light-based interventions present as alternative options over the past decade and have been used in combination with conventional pharmacological therapies and other physical modalities. An updated overview on the use of lasers and light-based devices in acne management is presented to help clinicians understand the safety and efficacy of these treatment options. The effectiveness of neodymium:yttrium aluminum garnet (Nd:YAG) for treating acne is supported by more high-level studies compared with other laser devices. There is limited evidence to support the use of CO 2 lasers, potassium titanyl phosphate lasers, and 1565-nm non-ablative fractional lasers for treating acne. Among light devices, photodynamic therapy is the most studied, showing higher efficacies than some of the conventional topical and oral acne therapies. Intense-pulsed light and blue light therapies also show favorable outcomes. A limitation is that most studies are non-randomized and lack a control group, and report on a variety of device settings, treatment regimens, and outcome measures, making it challenging to summarize and generalize findings. Although the use of laser and light devices to treat acne is promising, further work with randomized controlled study designs and larger sample sizes will provide improved guidance on the application of these modalities.

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An overview of treatment options for mild‐to‐moderate acne based on American Academy of Dermatology, European Academy of Dermatology and Venereology, and Italian Society of Dermatology and Venereology guidelines

Cited by 23 publications

References 30 publications

Comparison of dermatologists and family physicians in terms of prescribing antibiotics for the treatment of acne vulgaris

Comparison of dermatologists and family physicians in terms of prescribing antibiotics for the treatment of acne vulgaris

Topical antibiotics in the dermatological clinical practice: Indications, efficacy, and adverse effects

The Use of Lasers and Light Devices in Acne Management: An Update

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