An Overview of the Surgical Management of Hepatic Neuroendocrine Metastases

Abstract

Neuroendocrine tumours (NET) frequently metastasise to the liver (NLM) and are associated with significant morbidity and mortality. Numerous treatment options have been implemented both for cure, and to implement disease control. Surgical treatment includes curative resection, palliative cytoreductive resection and transplantation. Complete surgical resection is only possible in a subset of people with NLMs due to excessive metastatic burden and anatomical location. Ablative therapies may be used either as an adjunct to surgery or as a primary treatment. The purpose of the following article is to summarise surgical treatment strategies in the management of patients with hepatic neuroendocrine metastases, based on the available literature.

Theranostics Applications in Neuroendocrine Tumors of Thorax

“…Primer tümör rezeksiyonu yapılmış ancak karaciğer metastazı bulunan NET'lerde Y-90 mikroküre ile hepatik arter yolu ile radyoembolizasyon, kemo-embolizasyon ile radyofrekans ablasyon ve karaciğer transplantasyonu da seçilmiş hastalarda tedavi seçenekleri arasında önerilmektedir. Ancak bu konuda kesin bir uzlaşı bulunmamaktadır (12,13).…”