An Overview of Quinoline Derivatives as Anti-Cancer Agents
Mostafa Aref,
Abeer Mohamed,
Mohammed Dahab
et al.
Abstract:One of the most significant pharmacophoric cores in drug discovery in recent decades, notably in anticancer research, has been the quinoline scaffold. Many lead compounds with promising selective cytotoxic and immunomodulatory properties are discovered using quinoline derivatives. The review of the literature found that quinoline derivatives have the ability to inhibit protein kinases and other molecular targets. It was also designed to be involved in the disruption of tubulin assembly. The purpose of this rev… Show more
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