An overview of methods to mitigate artifacts in optical coherence tomography imaging of the skin

Abstract

Clinical dermatologists benefit from using these image enhancement algorithms to improve OCT diagnosis and essentially function as a noninvasive optical biopsy.

Refractive index correction in optical coherence tomography images of multilayer tissues

“…where z i is the thickness of the layer i [Eqs. (2) and (3)]E Q -T A R G E T ; t e m p : i n t r a l i n k -; e 0 0 2 ; 6 3 ; 4 4 6 Z ¼ 1 2 SL:t Z ;…”

“…where SL ∝ 1 RI is the speed of the light, and RI is the predefined refractive index of the corresponding medium, used by the OCT system. Equations (2) and (3) show that the travel time depends on the layer thicknesses and the refractive indices. For an accurate image reconstruction, it is necessary to have the exact value of the speed of light or the refractive index at each layer of a complex tissue.…”

“…Optical coherence tomography (OCT) is a high-resolution, noninvasive imaging modality with a large number of applications in the fields of ophthalmology and dermatology. [1][2][3] Light beams interact with microstructures in a complex tissue based on their optical properties. The beams entering the tissue, experience refraction, reflection, scattering, and absorption.…”

An Application of Simulated Annealing in Compensation of Nonlinearity of Scanners

“…The proposed method can be easily used in optical coherence tomography (OCT) and photoacoustic microscopy imaging techniques to acquire a more accurate images from the tissue microstructures [38][39][40][41][42][43].…”

Development of a Stationary 3D Photoacoustic Imaging System Using Sparse Single-Element Transducers: Phantom Study

“…Photoacoustic (PA) imaging is a fast-developing hybrid imaging modality that combines optical absorption and ultrasound detection techniques to visualize the hemodynamic changes in biological tissues [1][2][3][4][5][6][7]. In contrast to all-optical imaging methods [8][9][10], it uses light for illumination and ultrasound for detection. In PA imaging (PAI), a nanosecond pulsed laser deposits energy onto a tissue, causing a local temperature increase of light absorbing molecules and subsequent thermal expansion through the thermoacoustic effect [1,6,7,11].…”