“…Patients with GBM usually live 12-18 months after diagnosis. [1][2][3] The annual death rate in China is as high as 30 000, 4 which is associated with neoplastic glial cells such as oligodendrocytes, astrocytes, and ependymal cells. Currently, the prognosis for HGG remains bleak despite the available combination therapies, including surgery, radiotherapy, and chemotherapy.…”