Abstract:The last three decades have witnessed an increasing demand for novel analytical tools for the analysis of gases including odorants and volatile organic compounds (VOCs) in various domains. Traditional techniques such as gas chromatography coupled with mass spectrometry, although very efficient, present several drawbacks. Such a context has incited the research and industrial communities to work on the development of alternative technologies such as artificial olfaction systems, including gas sensors, olfactory… Show more
“…and anthropogenic (fossil fuels, automobile exhaust, etc.) [ 24 ]. Studies have shown that most VOCs have adverse effects on human health, causing symptoms such as headaches, and nose, eye and throat irritation [ 25 ].…”
Section: Advances In Electrochemical Signal Amplification Strategies ...mentioning
confidence: 99%
“…In addition, VOC and odor analysis can be used for quality assessment in the food, beverage, and flavor industries. Therefore, it is crucial to monitor the nature and concentration of these compounds in indoor or outdoor environments [ 24 ].…”
Section: Advances In Electrochemical Signal Amplification Strategies ...mentioning
Biosensors are powerful analytical tools used to identify and detect target molecules. Electrochemical biosensors, which combine biosensing with electrochemical analysis techniques, are efficient analytical instruments that translate concentration signals into electrical signals, enabling the quantitative and qualitative analysis of target molecules. Electrochemical biosensors have been widely used in various fields of detection and analysis due to their high sensitivity, superior selectivity, quick reaction time, and inexpensive cost. However, the signal changes caused by interactions between a biological probe and a target molecule are very weak and difficult to capture directly by using detection instruments. Therefore, various signal amplification strategies have been proposed and developed to increase the accuracy and sensitivity of detection systems. This review serves as a reference for biosensor and detector research, as it introduces the research progress of electrochemical signal amplification strategies in olfactory and taste evaluation. It also discusses the latest signal amplification strategies currently being employed in electrochemical biosensors for nanomaterial development, enzyme labeling, and nucleic acid amplification techniques, and highlights the most recent work in using cell tissues as biosensitive elements.
“…and anthropogenic (fossil fuels, automobile exhaust, etc.) [ 24 ]. Studies have shown that most VOCs have adverse effects on human health, causing symptoms such as headaches, and nose, eye and throat irritation [ 25 ].…”
Section: Advances In Electrochemical Signal Amplification Strategies ...mentioning
confidence: 99%
“…In addition, VOC and odor analysis can be used for quality assessment in the food, beverage, and flavor industries. Therefore, it is crucial to monitor the nature and concentration of these compounds in indoor or outdoor environments [ 24 ].…”
Section: Advances In Electrochemical Signal Amplification Strategies ...mentioning
Biosensors are powerful analytical tools used to identify and detect target molecules. Electrochemical biosensors, which combine biosensing with electrochemical analysis techniques, are efficient analytical instruments that translate concentration signals into electrical signals, enabling the quantitative and qualitative analysis of target molecules. Electrochemical biosensors have been widely used in various fields of detection and analysis due to their high sensitivity, superior selectivity, quick reaction time, and inexpensive cost. However, the signal changes caused by interactions between a biological probe and a target molecule are very weak and difficult to capture directly by using detection instruments. Therefore, various signal amplification strategies have been proposed and developed to increase the accuracy and sensitivity of detection systems. This review serves as a reference for biosensor and detector research, as it introduces the research progress of electrochemical signal amplification strategies in olfactory and taste evaluation. It also discusses the latest signal amplification strategies currently being employed in electrochemical biosensors for nanomaterial development, enzyme labeling, and nucleic acid amplification techniques, and highlights the most recent work in using cell tissues as biosensitive elements.
“…In the past decades the literature has reported novel VOC sensors and biosensors designed for solving these issues with remarkable results, as reported in different reviews and research papers [ 53 , 54 , 55 , 56 , 57 ]. In general, VOC sensors are devices capable of registering electrical, photophysical, mechanical, or biological changes, after the interaction with specific volatile compounds.…”
The efficient and selective detection of volatile organic compounds (VOCs) provides key information for various purposes ranging from the toxicological analysis of indoor/outdoor environments to the diagnosis of diseases or to the investigation of biological processes. In the last decade, different sensors and biosensors providing reliable, rapid, and economic responses in the detection of VOCs have been successfully conceived and applied in numerous practical cases; however, the global necessity of a sustainable development, has driven the design of devices for the detection of VOCs to greener methods. In this review, the most recent and innovative VOC sensors and biosensors with sustainable features are presented. The sensors are grouped into three of the main industrial sectors of daily life, including environmental analysis, highly important for toxicity issues, food packaging tools, especially aimed at avoiding the spoilage of meat and fish, and the diagnosis of diseases, crucial for the early detection of relevant pathological conditions such as cancer and diabetes. The research outcomes presented in the review underly the necessity of preparing sensors with higher efficiency, lower detection limits, improved selectivity, and enhanced sustainable characteristics to fully address the sustainable manufacturing of VOC sensors and biosensors.
“…In recent years, elastic sensitivity has been presented as a novel way to measure gases by a small shift in elastic properties of nanostructured layers [ 11 , 20 , 21 , 22 , 23 ]. Several studies to achieve sensors based on nanostructured sensitive layers had been performed [ 24 , 25 , 26 ], resulting in highly sensitive and selective sensors to improve electronic nose technology for detecting, discriminating and classifying target gases. For example, Bhasker et al [ 27 ] conclude that both mass loading and change in elasticity, are the sensing mechanisms in ammonia detection.…”
In this research, a compact electronic nose (e-nose) based on a shear horizontal surface acoustic wave (SH-SAW) sensor array is proposed for the NO2 detection, classification and discrimination among some of the most relevant surrounding toxic chemicals, such as carbon monoxide (CO), ammonia (NH3), benzene (C6H6) and acetone (C3H6O). Carbon-based nanostructured materials (CBNm), such as mesoporous carbon (MC), reduced graphene oxide (rGO), graphene oxide (GO) and polydopamine/reduced graphene oxide (PDA/rGO) are deposited as a sensitive layer with controlled spray and Langmuir–Blodgett techniques. We show the potential of the mass loading and elastic effects of the CBNm to enhance the detection, the classification and the discrimination of NO2 among different gases by using Machine Learning (ML) techniques (e.g., PCA, LDA and KNN). The small dimensions and low cost make this analytical system a promising candidate for the on-site discrimination of sub-ppm NO2.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.