An Overview of Adverse Drug Reaction Monitoring in China

Pharmacovigilance in China: issues of concern identified through an analysis of the Chinese Adverse Drug Reaction Information Bulletin 2001 to 2014

“…China has improved its pharmacovigilance considerably in recent years. Since the setting up of its National Center for Adverse Drug Reaction (ADR) Monitoring 1989, the Chinese government has developed it to include the legal requirements, the organizational system and the technical system . The rapid development of this system was prompted by public concern about ADR.…”

Drug Safety Surveillance in China and Other Countries: A Review and Comparison

“…At the foundation of China's drug safety surveillance program is its National Center for ADR Monitoring. As early as 1988, the national ADR monitoring project was initiated with the support of the China Ministry of Health (MOH), and involved 10 regional medical organizations within several cities and provinces, including Beijing, Shanghai, Hubei, Heilongjiang, and other provinces [4,5]. In late 1989, the National Center for ADR Monitoring was formally established and primarily focused on 85 hospitals nationwide that were responsible for monitoring ADR events [4,5].…”

“…As early as 1988, the national ADR monitoring project was initiated with the support of the China Ministry of Health (MOH), and involved 10 regional medical organizations within several cities and provinces, including Beijing, Shanghai, Hubei, Heilongjiang, and other provinces [4,5]. In late 1989, the National Center for ADR Monitoring was formally established and primarily focused on 85 hospitals nationwide that were responsible for monitoring ADR events [4,5]. In 1998, the National Center joined the World Health Organization's Collaborating Center for International Drug Monitoring (called the Uppsala Monitoring Center) [4,5].…”

“…In late 1989, the National Center for ADR Monitoring was formally established and primarily focused on 85 hospitals nationwide that were responsible for monitoring ADR events [4,5]. In 1998, the National Center joined the World Health Organization's Collaborating Center for International Drug Monitoring (called the Uppsala Monitoring Center) [4,5]. In 1999, the National Center for ADR Monitoring which also houses the Center for Drug Reevaluation (CDR) joined the SFDA and reports to both the SFDA and the MOH.…”

A strategy for the detection of quality fluctuation of a Chinese herbal injection based on chemical fingerprinting combined with biological fingerprinting

“…This has been a problem in the QC of herbal injections because unknown substances have resulted in adverse drug reactions and adverse drug events [13]. These include pyrogenic reactions, anaphylactic reactions, allergic shock, or even death [14,15]. Hence, it has become necessary to establish novel approaches for the QC of herbal injections from a biological viewpoint [16][17][18].…”