An Overview: Laser Applications in Dentistry

Jawad, Mohammed M.; AbdulQader, Sarah Talib; Zaidan, B. B.; Zaidan, A. A.; AbdulQader, Ibraheem T.; Naji, Ahmed Wathik

doi:10.3923/ijp.2011.189.197

Cited by 5 publications

(3 citation statements)

References 20 publications

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“…We utilized two custom‐built red light sources that differed in their power, LED emissions and other accompanying aspects to study their effects on the PDI of prions. Red light not only excites Pcs effectively but also allows better deep light penetration , which is important because prions are an inseparable part of tissues. The DALS array layout led to subtle differences in the light intensity and temperature of individual wells during the treatment, which may have contributed to the variability of the experimental results.…”

Section: Discussionmentioning

confidence: 99%

Optimization of the photodynamic inactivation of prions by a phthalocyanine photosensitizer: The crucial involvement of singlet oxygen

Kostelanská

Freisleben

Hanusova

et al. 2019

Journal of Biophotonics

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Prion disorders are fatal neurodegenerative diseases caused by the autocatalytic conversion of a natively occurring prion protein (PrP C ) into its misfolded infectious form (PrP TSE ). The proven resistance of PrP TSE to common disinfection procedures increases the risk of prion transmission in medical settings. Herein, we present the effective photodynamic inactivation (PDI) of prions by disulfonated hydroxyaluminum phthalocyanine (AlPcOH(SO 3 ) 2 ) utilizing two custom-built red light sources. The treatment eliminates PrP TSE signal in infectious mouse brain homogenate with efficiency that depends on light intensity but has a low effect on the overall protein content. Importantly, singlet oxygen (O 2 ( 1 Δ g )) is the only species significantly photogenerated by AlPcOH(SO 3 ) 2 , and it is responsible for the PDI of prions. More intensive light conditions show not only higher O 2 ( 1 Δ g ) production but also decreases in AlPcOH(SO 3 ) 2 photostability. Our findings suggest that PDI by AlPcOH(SO 3 ) 2 -generated O 2 ( 1 Δ g ) represents a promising approach for prion inactivation that may be useful in future decontamination strategies for delicate medical tools. K E Y W O R D S decontamination, photodynamic inactivation, phthalocyanines, prions, singlet oxygen

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Section: Discussionmentioning

confidence: 99%

Optimization of the photodynamic inactivation of prions by a phthalocyanine photosensitizer: The crucial involvement of singlet oxygen

Kostelanská

Freisleben

Hanusova

et al. 2019

Journal of Biophotonics

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“…The LLLT indicated that laser irradiation may have a beneficial effect on the wound healing of bone by increasing vascularization, 11 stimulating formation of trabecular osteoid tissue, promoting faster tissue metabolism, and increasing the reaction of bone callus, which will lead to the acceleration of bone regeneration. 12,13 Since bone remodeling in orthodontic treatment comprises modification to the dentoalveolar structure, the effect of LLLT on orthodontics induced interest amongst the researchers.…”

Section: Introductionmentioning

confidence: 99%

Effect of 940 nm low-level laser therapy on osteogenesisin vitro

et al. 2013

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Bone regeneration is essential in medical treatment, such as in surgical bone healing and orthodontics. The aim of this study is to examine the effect of different powers of 940 nm diode low-level laser treatment (LLLT) on osteoblast cells during their proliferation and differentiation stages. A human fetal osteoblast cell line was cultured and treated with LLLT. The cells were divided into experimental groups according to the power delivered and periods of exposure per day for each laser power. The (3-(4,5-dimethylthiazol-2yl)-2,5 diphenyl tetrazolium bromide) (MTT) assay was used to determine cell proliferation. Both alkaline phosphatase and osteocalcin activity assays were assessed for cell differentiation. All treatment groups showed a significant increase in cell proliferation and differentiation compared to the control group. Regarding the exposure time, the subgroups treated with the LLLT for 6 min showed higher proliferation and differentiation rates for the powers delivered, the 300-mW LLLT group significantly increased the amount of cell proliferation. By contrast, the 100 and 200 mW groups showed significantly greater amounts of cell differentiation. These results suggest that the use of LLLT may play an important role in stimulating osteoblast cells for improved bone formation.

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“…by promising the operator of a complete bloodless, painless, clock instant and most importantly a sterile field to play safe. 5 Lasers are now a promising viable and available system representing the "NEW BIOLOGIQUE" of Dentistry with a high state of technical refinement in terms of both performance and user friendly at the same time. Realizing the need of the hour to introduce lasers into the latest day high class dentistry, our institute, I.T.S.C.D.S.R, has not wasted time in acquiring this technology and has incorporated its use to the epitome in each and every aspect of dentistry at graduate as well as post graduate level.…”

mentioning

confidence: 99%

Lasers- Hallmark lineage of clinical dentistry

2020

JDS

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An Overview: Laser Applications in Dentistry

Cited by 5 publications

References 20 publications

Optimization of the photodynamic inactivation of prions by a phthalocyanine photosensitizer: The crucial involvement of singlet oxygen

Optimization of the photodynamic inactivation of prions by a phthalocyanine photosensitizer: The crucial involvement of singlet oxygen

Effect of 940 nm low-level laser therapy on osteogenesisin vitro

Lasers- Hallmark lineage of clinical dentistry

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