An Outbreak of Q Fever Probably Due to Contact with a Parturient Cat

Marrie, Thomas J.; MacDonald, A.C.; Durant, Heather; Yates, Linda; McCormick, Leo

doi:10.1378/chest.93.1.98

Cited by 76 publications

(48 citation statements)

References 15 publications

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“…Although dyspnea was an associated feature of our outbreak, only one of eight patients with X rays had pneumonia. This is in contrast to what is typically seen in Nova Scotia, where C. burnetii pneumonia is common after exposure to infected parturient cats (15,23).…”

Section: Resultscontrasting

confidence: 82%

See 1 more Smart Citation

Goat-Associated Q Fever: A New Disease in Newfoundland

Hatchette

Hudson

Schlech

et al. 2001

Emerg. Infect. Dis.

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106

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Section: Resultscontrasting

confidence: 82%

“…Antibody titers (immunoglobulin G [IgG]) to C. burnetii phase I and phase II antigens were determined (15). Antibodies were detected by using indirect immunofluorescence with whole cells of the Nine-Mile strain of C. burnetii.…”

Section: Laboratory Studiesmentioning

confidence: 99%

Goat-Associated Q Fever: A New Disease in Newfoundland

Hatchette

Hudson

Schlech

et al. 2001

Emerg. Infect. Dis.

Self Cite

106

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“…Other modes of transmission that have been described recently include exposure to parturient cats (42,48,57) and wild rabbits (49), urban exposure to manure brought from farms as fertilizer (64), and residence along the route of a sheep drive (18).…”

Section: Microbiologymentioning

confidence: 99%

Q fever

Reimer

1993

Clin Microbiol Rev

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Q fever is an acute febrile illness first described in 1935 and now seen in many parts of the world. Human infection follows exposure to animals, especially domestic livestock. Recent outbreaks in metropolitan areas have implicated cats as the carrier of disease to humans. The etiologic agent, Coxiella burnetti, belongs to the family Rickettsiaceae, although it has distinct genetic characteristics and modes of transmission. Most recent attention has been focused on a number of large outbreaks of Q fever associated with medical research involving pregnant sheep. Although most infections are self-limited, some patients require prolonged treatment. Recent vaccines have had encouraging success in the prevention of disease in individuals at high risk of exposure.

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“…year Ref. cattle and cats (van Moll et al 1993;Guatteo et al 2011;Berri et al 2001;Berri et al 2002;Hatchette et al 2003;Rousset et al 2009;Lang 1990;Marrie et al 1988b). Abortion occurs most frequently at the end of gestation, without preceding clinical symptoms (Arricau-Bouvery and Rodolakis 2005).…”

Section: Based Onmentioning

confidence: 99%

Q Fever (Coxiella burnetii): A Blueprint for Outbreaks

Roest

Frangoulidis

2014

Zoonoses - Infections Affecting Humans and Animals

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About 80 years ago, Q fever research began due to human outbreaks of unknown origin, associated with domestic animals. Since then, some but not all characteristics of this "query" disease, caused by the intracellular bacterium Coxiella burnetii were revealed. In this chapter the bacteriology of the bacterium, clinical presentation, epidemiology and transmission of the disease in humans and animals are presented. Domestic small ruminants are the main source of human Q fever. Although Q fever is considered to be an occupational disease, outbreaks have a major public health impact and attract most attention. The Dutch Q fever outbreak, involving 4000 human cases over the years [2007][2008][2009][2010], is an example of how Q fever can re-emerge from an endemic state into an outbreak of unforeseen dimension. In this outbreak the epidemiological link between dairy goats and human cases was confirmed by genotyping for the first time. This was possible due to the previous development of genotyping assays that are applicable on clinical material. Although Q fever seems to be a blue print for outbreaks it is not known yet what factors are essential to cause outbreaks and how they interact. To prevent outbreaks, a better understanding of these factors and their interaction is necessary and research should therefore focus on this.

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An Outbreak of Q Fever Probably Due to Contact with a Parturient Cat

Cited by 76 publications

References 15 publications

Goat-Associated Q Fever: A New Disease in Newfoundland

Goat-Associated Q Fever: A New Disease in Newfoundland

Q fever

Q Fever (Coxiella burnetii): A Blueprint for Outbreaks

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