An Outbreak of Arsenical Dermatoses in a Mining Community

Birmingham, Donald J.

doi:10.1001/archderm.1965.01600110043010

Cited by 38 publications

(3 citation statements)

References 6 publications

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“…Thus, occupational exposure has been reported to cause sensitisation dermatitis (Holmqvist, 1951;Pinto and McGill, 1953;Birmingham et al, 1965), and ulceration or perforation of the nasal septum (Birmingham et al, 1965). Electrocardiographic changes and circulatory impairment resulting in finger gangrene have also been observed (Butzengeiger, 1940;Glazener et al, 1968).…”

mentioning

confidence: 99%

Arsenic exposure and mortality: a case-referent study from a Swedish copper smelter.

Axelson¹,

Dahlgren²,

Jansson³

et al. 1978

Occupational and Environmental Medicine

124

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mentioning

confidence: 99%

Arsenic exposure and mortality: a case-referent study from a Swedish copper smelter.

Axelson¹,

Dahlgren²,

Jansson³

et al. 1978

Occupational and Environmental Medicine

124

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“…Table 4. Birmingham et al (5) reported an outbreak of contact arsenic skin disease observed on a metal smelter and family members in the adjoining mining community. Typical chronic arsenic poisoning was observed, especially on the skin and mucous membrane, was observed only in the roasters, whereas among miners, ore dressers, and clerical workers, symptoms and signs of chronic arsenic poisoning could not be detected.…”

Section: ) History Of Symptoms Of Chronic Bronchitis and Pneumoconiomentioning

confidence: 99%

Outbreak of Chronic Arsenic Poisoning among Retired Workers from an Arsenic Mine in Japan

Ishinishi¹,

Kodama²,

Nobutomo³

et al. 1977

Environmental Health Perspectives

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JSTOR is a not-for-profit service that helps scholars, researchers, and students discover, use, and build upon a wide range of content in a trusted digital archive. We use information technology and tools to increase productivity and facilitate new forms of scholarship. For more information about JSTOR, please contact support@jstor.org.. The National Institute of Environmental Health Sciences (NIEHS) andBrogan & Partners are collaborating with JSTOR to digitize, preserve and extend access to Environmental Health Perspectives.Reffred former workers of Matsuo Arsenic Mine of Miyazaki prefecture in Japan were subjected to extensive medical examination. The number of retired workers subjected to examination were 61 of 208 workers who were engaged in the works of the mine and were tracked down by the work rolls. These workers left the mine more than 15 years prior to the time of the examination. The main works in the mine were classiffed as mining, dressing of ores, refining, and clerical work. Several findings such as arsenodermatitis, depigmentation, perforation of nasal septum, hyposmia, anosmia, and peripheral nervous disturbance attributed to exposure to arsenic were observed in 9 of 21 roasters who often worked in the arsenic kitchen. No characteristic findings of arsenic poisoning, that is, gastrointestinal disturbances disorder of the cardiovascular system, hematopoietic disorders or liver disturbance were observed in the retired workers. Another notable finding was that 8 cases diagnosed as pneumoconiosis were found in 18 miners.

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“…Arsenic is a toxic metalloid element which is an acute and chronic intracellular poison for humans [Schiller e t al, 1977;Brown et al, 19761. Acute arsenic exposure causes a variety of nonspecific complaints in low doses and, in higher doses, leads to nausea, vomiting, and death [Buchanan, 19621. Chronic exposure leads to weight loss, skin abnormalities including pigment changes, keratoses and folliculitis [Birmingham et al, 1965;Perry et al, 19481, conjunctival and respiratory irritation, nasal septa1 perforation [Buchanan, 19621, impairment of hematopoiesis Kyle and Pease, 19651, and sensory peripheral neuropathy [Heyman et al, 1956;Landau et al, 19771. Chronic arsenic exposure has also been linked with cancer of the skin [Hill and Faning, 1948;Tseng et all, lung [Milham and Strong, 1974;Ott et al, 19741, liver [Lander et al, 1975;Roth, 19571, and possibly lymphatic tissue [Ott et al, 19741. Salts of arsenic are widely used as wood preservatives, but the health hazards of arsenic exposure for workers exposed occupationally to treated wood have not been defined.…”

Section: Introductionmentioning

confidence: 99%

Low‐level arsenic exposure in wood processing plants

Rosenberg

Landrigan

Crowley

1980

American J Industrial Med

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In October 1978, seven construction workers building a pier in Monterey, California, developed symptoms consistent with arsenic intoxication and had elevated urinary levels of arsenic. The wood used for the pier had been pressure-treated with an arsenic preservative. To evaluate the potential acute medical hazards of preserving wood with arsenic, we evaluated employees at three California plants where arsenic preservatives are mixed and applied to wood. Histories, physical examinations, and urine specimens for arsenic analysis were collected from 44 workers exposed to arsenic and from 37 controls in three woodworking plants where arsenic is not used. A comparison of the groups failed to show any significant differences in history or physical examination. Adjustment for age, length of employment, and smoking histories did not alter the pattern. Urinary arsenic concentration was found to increase with increased exposure. These results do not imply absence of chronic or delayed toxicity, nor do they preclude the presence of a more subtle toxicity such as nerve conduction deficits. The data indicate existence of an arsenic exposure hazard in wood processing.U

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An Outbreak of Arsenical Dermatoses in a Mining Community

Cited by 38 publications

References 6 publications

Arsenic exposure and mortality: a case-referent study from a Swedish copper smelter.

Arsenic exposure and mortality: a case-referent study from a Swedish copper smelter.

Outbreak of Chronic Arsenic Poisoning among Retired Workers from an Arsenic Mine in Japan

Low‐level arsenic exposure in wood processing plants

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