An outbreak of acinetobacter septicaemia in a neonatal intensive care unit

Ng, P. C.; Herrington, R.A.; Beane, C.A.; Ghoneim, A T; Dear, P. R. F.

doi:10.1016/0195-6701(89)90077-7

Cited by 39 publications

(23 citation statements)

References 5 publications

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“…Among 8 strains of this clone, 6 were from neonates and one from a one-year-old aged infant. As previously reported neonates represent an important group of patients susceptible to the acquisition of bacteremia by Acinetobacter 18,22 . Among 76 studied strains, 15 were from neonates, four of them with bacteremia.…”

Section: Discussionmentioning

confidence: 88%

Biotyping, serotyping and ribotyping as epidemiological tools in the evaluation of Acinetobacter baumannii dissemination in hospital units, Sorocaba, São Paulo, Brazil

Gonçalves

Vaz

Araújo

et al. 2000

Rev. Inst. Med. trop. S. Paulo

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Dissemination of Acinetobacter baumannii strains in different units of a hospital in Sorocaba, São Paulo, Brazil was evaluated over a period of two years. By using biotyping, serotyping and ribotyping, 27 distinct clones were differentiated among 76 strains isolated between 1993-94, from clinical specimens of hospitalized patients. Two clones, 2:O4:A (biotype:serotype:ribotype) and 2:O29:A accounted for the majority of strains widely disseminated in the units during 1993. The introduction in the hospital setting, of a new clone, 6:O13:B, at the end of 1993 and its predominance through 1994 is discussed. Among 15 strains isolated from neonates, 6 (40%) belonged to the same clone, 2:O4:A. Interestingly, this clone was almost all recovered in neonatal intensive care unit, nursery and in pediatric unit. All strains were susceptible to imipenem and polymyxcin B. Multiresistant strains (up to 12 antimicrobial agents) accounted for 66.7% and 84.8% of the strains isolated in 1993 and in 1994, respectively.

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Section: Discussionmentioning

confidence: 88%

Biotyping, serotyping and ribotyping as epidemiological tools in the evaluation of Acinetobacter baumannii dissemination in hospital units, Sorocaba, São Paulo, Brazil

Gonçalves

Vaz

Araújo

et al. 2000

Rev. Inst. Med. trop. S. Paulo

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“…Diğer Acinetobacter türleri olan Acinetobacter lwoffii ve Acinetobacter junii, daha az sıklıkla izole edilmektedir ve tesadüfen enfeksiyonla ilişkili bulunmaktadır (5,6). Yenidoğan yoğun bakım kliniklerinde çeşitli Acinetobacter enfeksiyonları tanımlanmıştır (4)(5)(6)(7)(8)(9)(10)(11).…”

Section: Discussionunclassified

“…Bu rapor, YYBÜ'nde yaşanan Acinetobacter junii kaynaklı bir mini epideminin sunulduğu ikinci klinik çalışmadır (11).…”

Section: Discussionunclassified

Mini Epidemic of Acinetobacter Junii in a Neonatal Intensive Care Unit: Risk Factors and Control Procedures

Sandal¹,

Çetin²,

Özen³

et al. 2015

jpr

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“…Various Acinetobacter infections in neonatal wards have been described (4)(5)(6)(7)(8)(9)(10). They originated from air humidifiers, resuscitation bags, the intestinal flora of the neonates or from unknown sources and were sustained by spread via the hands of staff and contaminated equipment.…”

mentioning

confidence: 99%

“…Ng et al have described an outbreak of sepsis in neonates caused by Acinetobacter calcoaceticus var. lwoffii in which contaminated parenteral nutritional fluid was implicated as the possible source (10).…”

mentioning

confidence: 99%

Acinetobacter junii causes life-threatening sepsis in preterm infants

et al. 1999

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Acinetobacter junii caused sepsis in six preterm infants in our neonatal unit within 48 h. Each infant with clinical signs of systemic infection and activation of the acute phase response had two positive blood cultures with Acinetobacter junii. The sudden onset, the short duration of the outbreak and the fact that none of the infants were colonized by A. junii suggested a common source of A. junii administered directly into the blood. The only feature shared by all six affected newborns was an intravenous fat emulsion (Intralipid 10%), which was shown to be an excellent growth medium for A. junii. Sepsis did not occur in four infants with 20% fat emulsion or amino acids only. Vaminolact did not support growth of the outbreak strain. The immediate source of the outbreak could not be identified: samples of the actual feeds given were not available for investigation, but A. junii was not isolated from parenteral solutions with identical batch numbers used in the septic infants. We conclude that Acinetobacter junii can cause a life-threatening infection in preterm neonates. Contaminated intravenous fat emulsion is implicated as a possible source of the infection. As a part of rigid infection control, intravenous feedings should be prepared under aseptic conditions.

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An outbreak of acinetobacter septicaemia in a neonatal intensive care unit

Cited by 39 publications

References 5 publications

Biotyping, serotyping and ribotyping as epidemiological tools in the evaluation of Acinetobacter baumannii dissemination in hospital units, Sorocaba, São Paulo, Brazil

Biotyping, serotyping and ribotyping as epidemiological tools in the evaluation of Acinetobacter baumannii dissemination in hospital units, Sorocaba, São Paulo, Brazil

Mini Epidemic of Acinetobacter Junii in a Neonatal Intensive Care Unit: Risk Factors and Control Procedures

Acinetobacter junii causes life-threatening sepsis in preterm infants

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