An optimized polymeric delivery system for piggyBac transposition
Daniel Nisakar Meenakshi Sundaram,
Remant Bahadur K. C.,
Wei Fu
et al.
Abstract:The piggyBac transposon/transposase system has been explored for long‐term, stable gene expression to execute genomic integration of therapeutic genes, thus emerging as a strong alternative to viral transduction. Most studies with piggyBac transposition have employed physical methods for successful delivery of the necessary components of the piggyBac system into the cells. Very few studies have explored polymeric gene delivery systems. In this short communication, we report an effective delivery system based o… Show more
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