volume 6, issue 66, P61458-61467 2016
DOI: 10.1039/c6ra09812f
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Abstract: This article is dedicated to Professor Dieter Seebach, in recognition for his great contribution in Organic ChemistryWe revisited the classical synthetic procedure for Imatinib synthesis providing an improved and optimized approach in the preparation of a series of new Imatinib analogues. The proposed methodology effectively overcomes certain problematic steps, saves time and labor, provides a very high yield and purity and has the potential to be used for the synthesis of many analogues. Τhe formation of the…

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