An Optimized and Well-Characterized Niosome-Based Nanocarrier for Letrozole: A Brand- New Hybrid Therapy for Breast Cancer

Ahmadi, Saeedeh; Akbarzadeh, Iman; Chiani, Mohsen; Seraj, Mahmoud; Noorbazargan, Hassan; Saffar, Samaneh; Quazi, Sameer; Far, Bahareh Farasati

doi:10.21203/rs.3.rs-1197164/v1

Cited by 2 publications

(1 citation statement)

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“…In 2018, there were around two million new cases and 626,700 deaths, accounting for 25% of all cancer cases and 15% of all women. Cancer-related mortality in women [35,36]. Early detection of breast cancer lowers long-term death rates, however it has limits in terms of identifying early-stage cancer cells [37].…”

Section: Multiple Breast Cancer Biomarker Detectionmentioning

confidence: 99%

The Potential Implementation of Biosensors for the Diagnosis of Biomarkers of Various Cancer

Quazi¹

2022

Preprint

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In the era of nanotechnology, researchers are implementing point to care service to cancer patients to detect malignancy beforehand and to reduce the mortality rate of cancers. Cancer is known to be the most fatal disease among all other diseases and the survivability from cancer is quite impossible if the stage of the cancer is an advanced level. Though the early detection of cancer can increase the chances of survival with a double fold. Biosensor is a part of nanotechnology which is capable to provide point to care service in the field of medicine. With the rising number of cancer occurrences being identified around the world and the increasing number of deaths because of the identification of advanced cancer, biosensors can play a significant part in the early detection of cancer. New molecular methods, including as genomic and proteomic approaches, are increasingly being used to study patient molecular profiles. When such diagnosis method is paired with bioinformatics tools, they generate new data that can be used to discover new disease biomarkers. Finding precise and sensitive indicators that are corelated to a specific disease, as with many other diseases, can be challenging. Furthermore, the concentration of biomarkers in biological fluids varies according to illness states and phases. Peptides, proteins, up or down regulated expression of gene markers, and gene alternation are all examples of molecular markers that are commonly used to diagnose cancer. In this article, we have highlighted six different deadliest cancers such as Ovarian, Breast, Prostrate, Lung, Colorectal and Liver cancer. The article contains distinct types of biomarkers which are normally found in these kinds of cancer and generally used as a potential diagnostic target in the medicine field. The article mainly summarized the application of different types of biosensors devices in the detection of the mostly found biomarkers in the above cancer types.

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Section: Multiple Breast Cancer Biomarker Detectionmentioning

confidence: 99%