We study the long time behavior of the Hesse-Koszul flow on compact Hessian manifolds. When the first affine Chern class is negative, we prove that the flow converges to the unique Hesse-Einstein metric. We also derive a convergence result for a twisted Hesse-Koszul flow on any compact Hessian manifold. These results give alternative proofs for the existence of the unique Hesse-Einstein metric by Cheng-Yau and Caffarelli-Viaclovsky as well as the real Calabi theorem by Cheng-Yau, Delanoë and Caffarelli-Viaclovsky.