An optimal control model of the treatment of chronic Chlamydia trachomatis infection using a combination treatment with antibiotic and tryptophan

Akinlotan, Morenikeji Deborah; Mallet, Daniel G.; Araujo, Robyn P.

doi:10.1016/j.amc.2019.124899

Cited by 1 publication

(1 citation statement)

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“…[ 6 ] were defined as an optimal control derivation for the Chlamydia modeling. In [ 7 ], an optimal control modeling of the chronic Chlamydia trachomatis disease considering a combination treatment with tryptophan and antibiotic was derived. In [ 8 ], mathematical modeling of Chlamydia trachomatis in a human carrier was introduced.…”

Section: Introductionmentioning

confidence: 99%

Role of fractional derivatives in the mathematical modeling of the transmission of Chlamydia in the United States from 1989 to 2019

Vellappandi¹,

Kumar

Govindaraj³

2022

Nonlinear Dyn

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Nowadays, the mathematical modeling of infectious diseases is a big trend worldwide. The mathematical models help us to forecast future outbreaks of diseases in the presence of present data. In this article, we represent a model of the transmission of Chlamydia in the United States by using data from 1989 to 2019. In the formulation of the model, we used integer and fractional derivatives. Several graphs are plotted for the various possible cases of the given parameters. The aim of this paper is to justify how the mathematical models in terms of fractional derivatives have more degree of freedom to explore disease dynamics for a particular data set and capture memory effects. The separate parameter estimation for each value of the fractional order increases the novelty of this work. The use of a real-data set of Chlamydia in the United States makes this study more visible and important to the literature.

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Section: Introductionmentioning

confidence: 99%