An Optical Universal Plasmon-Based Biosensor for Virus ‎‎Detection

Abstract

Purpose Kretschmann-configuration has been used as a subwavelength framework to detect tiny ‎alterations of the refractive index of biomaterials. However, most of the theoretical assessment of such configuration ‎is usually based on the plane wave excitation transfer matrix method (TMM) of prism-‎coupled to thin metal film supporting plasmonic modes. Accordingly, a better theoretical framework ‎than the plane wave approximation is indispensable for reliable and accurate assessments and ‎simulations. A reformulated form of the traditional FFT-BPM has been adapted to evaluate the performance and characteristics of surface plasmonic waveguide biosensor. Method Surface plasmon mode is excited by a sub-wavelength narrow light beam. The highly confined optical energy of that plasmonic mode enables an ‎efficient means to detect tiny variations in the composition of ‎the analyte in contact with the metallic layer of the surface plasmon ‎guide. The plasmonic guided power is detected thereafter electronically via an optical MOS capacitor. Results the guided plasmonic power has been used to assess the fundamental characteristics and performance of the sensor, namely the linearity, sensitivity, and figure of merit as well as the full width at half maximum (FWHM). Conclusion The proposed sensor could be integrated to a wide class of angular measurement system (for instance goniometer) or via electronic detection of the optical plasmonic guided power. we claim that this work is worthy of being shared with researchers and ‎developers interested in the experimentation and assessment of sensitive biosensors; especially in ‎case when complicated and sophisticated analysis tools represent an unpleasant burden.

A Fiber-Optical Dosimetry Sensor for Gamma-Ray Irradiation Measurement in Biological Applications

“…Radiation dosimetry is the magnitude of the irradiated radiation dose received by a body/matter arising from exposure to high-energy radiation such as X-ray, gamma ray, etc. Several methods exist for radiation measurement such as optically stimulated luminescence (OSL) [1], thermo-luminescence (TL) [2], radio-luminescence (RL) [3], and semiconductor-based devices and chemical materials [4][5][6]. Currently, optical fiber-based dosimeters present a high potency to act as thermoluminescence dosimeters (TLD) in many applications [7][8][9][10].…”