An opinion paper on the maintenance of robustness: Towards a multimodal and intergenerational approach using digital twins

Vidal, Pierre‐Paul; Vienne-Jumeau, Aliénor; Moreau, Albane; Vidal, Catherine; Wang, Danping; Audiffren, Julien; Bargiotas, Ioannis; Barrois, Rémi; Buffat, Stéphane; Dubost, C; Ghidaglia, Jean‐Michel; Labourdette, Christophe; Mantilla, José Iván Alfonso; Oudre, Laurent; Quijoux, Flavien; Robert, Matthieu P.; Yelnik, A.; Ricard, Damien; Vayatis, Nicolas

doi:10.1002/agm2.12115

Cited by 6 publications

(19 citation statements)

References 51 publications

(98 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…As part of a wider project aiming to develop a numeric tool for individual longitudinal monitoring using quantitative approaches ( 58 ), the objective of the Postadychute-AG clinical trial is to validate the reliability of predictive models previously published ( 59 – 63 ) on prospective follow-up of institutionalized older adults and to quantify their sensitivity to physical rehabilitation. In order to achieve this objective, the risk of falls predicted each month by means of instrumental assessment of balance and gait, respectively, via posturography and ILG, will be compared with the number of falls actually recorded during that month by the nursing home's medical staff.…”

Section: Methods and Designmentioning

confidence: 99%

Postadychute-AG, Detection, and Prevention of the Risk of Falling Among Elderly People in Nursing Homes: Protocol of a Multicentre and Prospective Intervention Study

Quijoux

Bertin-Hugault²,

Zawieja³

et al. 2021

Front. Digit. Health

Self Cite

View full text Add to dashboard Cite

Introduction: While falls among the elderly is a public health issue, because of the social, medical, and economic burden they represent, the tools to predict falls are limited. Posturography has been developed to distinguish fallers from non-fallers, however, there is too little data to show how predictions change as older adults' physical abilities improve. The Postadychute-AG clinical trial aims to evaluate the evolution of posturographic parameters in relation to the improvement of balance through adapted physical activity (APA) programs.Methods: In this prospective, multicentre clinical trial, institutionalized seniors over 65 years of age will be followed for a period of 6 months through computer-assisted posturography and automatic gait analysis. During the entire duration of the follow-up, they will benefit from a monthly measurement of their postural and locomotion capacities through a recording of their static balance and gait thanks to a software developed for this purpose. The data gathered will be correlated with the daily record of falls in the institution. Static and dynamic balance measurements aim to extract biomechanical markers and compare them with functional assessments of motor skills (Berg Balance Scale and Mini Motor Test), expecting their superiority in predicting the number of falls. Participants will be followed for 3 months without APA and 3 months with APA in homogeneous group exercises. An analysis of variance will evaluate the variability of monthly measures of balance in order to record the minimum clinically detectable change (MDC) as participants improve their physical condition through APA.Discussion: Previous studies have stated the MDC through repeated measurements of balance but, to our knowledge, none appear to have implemented monthly measurements of balance and gait. Combined with a reliable measure of the number of falls per person, motor capacities and other precipitating factors, this study aims to provide biomechanical markers predictive of fall risk with their sensitivity to improvement in clinical status over the medium term. This trial could provide the basis for posturographic and gait variable values for these elderly people and provide a solution to distinguish those most at risk to be implemented in current practice in nursing homes.Trial Registration: ID-RCB 2017-A02545-48.Protocol Version: Version 4.2 dated January 8, 2020.

show abstract

Section: Methods and Designmentioning

confidence: 99%

Postadychute-AG, Detection, and Prevention of the Risk of Falling Among Elderly People in Nursing Homes: Protocol of a Multicentre and Prospective Intervention Study

Quijoux

Bertin-Hugault²,

Zawieja³

et al. 2021

Front. Digit. Health

Self Cite

View full text Add to dashboard Cite

show abstract

“…It seamlessly connected the physical world and digital world, effectively integrated information [91], provided real-time monitoring of patient body data [92], enabled more real-time relevant medical responses [87], and improved resource utilization rate [86]. Researchers also achieved predictive maintenance for the elderly [90] by combining HDT with healthcare, providing more accurate and faster services for elderly healthcare [6]. Furthermore, HDT is expected to achieve better disease prediction, disease diagnosis, disease treatment, continuous monitoring, medical assessment, and risk assessment without interfering with patients' daily activities [86] [5].…”

Section: Healthcare Domainmentioning

confidence: 99%

Human Digital Twin: A Survey

Lin

Chen

Ali

et al. 2022

Preprint

View full text Add to dashboard Cite

Digital twin has recently attracted growing attention, leading to intensive research and applications. Along with this, a new research area, dubbed as "human digital twin" (HDT), has emerged. Similar to the conception of digital twin, HDT is referred to as the replica of a physical-world human in the digital world. Nevertheless, HDT is much more complicated and delicate compared to digital twins of any physical systems and processes, due to humans' dynamic and evolutionary nature, including physical, behavioral, social, physiological, psychological, cognitive, and biological dimensions. Studies on HDT are limited, and the research is still in its infancy. In this paper, we first examine the inception, development, and application of the digital twin concept, providing a context within which we formally define and characterize HDT based on the similarities and differences between digital twin and HDT. Then we conduct an extensive literature review on HDT research, analyzing underpinning technologies and establishing typical frameworks in which the core HDT functions or components are organized. Built upon the findings from the above work, we propose a generic architecture for the HDT system and describe the core function blocks and corresponding technologies. Following this, we present the state of the art of HDT technologies and applications in the healthcare, industry, and daily life domain. Finally, we discuss various issues related to the development of HDT and point out the trends and challenges of future HDT research and development.

show abstract

“…Rehabilitation, for purely economic reasons, is still largely under-dosed. With the ageing of the population and the problem of maintaining autonomy, this policy is no longer tenable (Vidal et al 2020 ). Personalized approaches along with precision diagnostics will pave the way to many improved treatments.…”

Section: Perspectivesmentioning

confidence: 99%

“…In the same way, the occurrence of pathologies can profoundly alter motor responses and the underlying sensorimotor transformations. Therefore, individual longitudinal monitoring or follow-up of persons using quantitative approaches based on individual markers of behavior becomes imperative (Vidal et al 2020 ).…”

Section: Introductionmentioning

confidence: 99%

Perceptual-motor styles

Vidal

Lacquaniti

2021

Exp Brain Res

Self Cite

View full text Add to dashboard Cite

Even for a stereotyped task, sensorimotor behavior is generally variable due to noise, redundancy, adaptability, learning or plasticity. The sources and significance of different kinds of behavioral variability have attracted considerable attention in recent years. However, the idea that part of this variability depends on unique individual strategies has been explored to a lesser extent. In particular, the notion of style recurs infrequently in the literature on sensorimotor behavior. In general use, style refers to a distinctive manner or custom of behaving oneself or of doing something, especially one that is typical of a person, group of people, place, context, or period. The application of the term to the domain of perceptual and motor phenomenology opens new perspectives on the nature of behavioral variability, perspectives that are complementary to those typically considered in the studies of sensorimotor variability. In particular, the concept of style may help toward the development of personalised physiology and medicine by providing markers of individual behaviour and response to different stimuli or treatments. Here, we cover some potential applications of the concept of perceptual-motor style to different areas of neuroscience, both in the healthy and the diseased. We prefer to be as general as possible in the types of applications we consider, even at the expense of running the risk of encompassing loosely related studies, given the relative novelty of the introduction of the term perceptual-motor style in neurosciences.

show abstract

An opinion paper on the maintenance of robustness: Towards a multimodal and intergenerational approach using digital twins

Abstract: This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

Cited by 6 publications

References 51 publications

Postadychute-AG, Detection, and Prevention of the Risk of Falling Among Elderly People in Nursing Homes: Protocol of a Multicentre and Prospective Intervention Study

Postadychute-AG, Detection, and Prevention of the Risk of Falling Among Elderly People in Nursing Homes: Protocol of a Multicentre and Prospective Intervention Study

Human Digital Twin: A Survey

Perceptual-motor styles

Contact Info

Product

Resources

About