2013
DOI: 10.1016/j.jtcvs.2012.04.020
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An open randomized controlled trial of median sternotomy versus anterolateral left thoracotomy on morbidity and health care resource use in patients having off-pump coronary artery bypass surgery: The Sternotomy Versus Thoracotomy (STET) trial

Abstract: Chanoit graduated from the Veterinary School of Toulouse, France. After holding academic positions in France and in the United States, Guillaume came to the UK in 2011, taking up the position of Senior Lecturer in Small Animal Soft Tissue Surgery at the University of Bristol. He is also a member of the Bristol Heart Institute where he undertakes a large portion of his research. Guillaume has a particular interest in cardiothoracic surgery. He is a JSAP Associate Editor for soft tissue surgery.

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Cited by 56 publications
(55 citation statements)
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References 32 publications
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“…RA-MIDCAB entails a shorter intubation time and a shorter stay at post-operative care units, with more patients transferred post-operatively to the PACU (fast-track treatment). These findings are in line with previous studies [26,27]. Hospital length of stay (LOS), however, showed no significant difference between the two study groups.…”
Section: Comparison Of Minimally Invasive and Conventional Coronary Asupporting
confidence: 92%
“…RA-MIDCAB entails a shorter intubation time and a shorter stay at post-operative care units, with more patients transferred post-operatively to the PACU (fast-track treatment). These findings are in line with previous studies [26,27]. Hospital length of stay (LOS), however, showed no significant difference between the two study groups.…”
Section: Comparison Of Minimally Invasive and Conventional Coronary Asupporting
confidence: 92%
“…On the assumption that there would be a moderate correlation of 0.7 between pre-and post-intervention measures and between repeated post-intervention measures, as observed in previous work, 267 and on the basis that there would be one baseline and five postoperative measures, we estimated that a sample size of 150 patients would enable us to detect a small to moderate target difference between groups of 0.4, with 90% power and 5% significance (two-tailed). We aimed to recruit 170 participants (85 per group), assuming an attrition rate of between 10% and 15% for incomplete sampling, participant death and withdrawal.…”
Section: Sample Size Considerationsmentioning
confidence: 86%
“…We therefore estimated that a sample size of 60 participants would be able to provide insight into the process underlying measured differences in the primary or other clinical outcomes, as was our experience previously. 267 …”
Section: Sample Size Considerationsmentioning
confidence: 99%
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“…Studies that evaluated the circulating levels of proinflammatory cytokines (IL‐6, ‐8, and ‐10) after off‐ and on‐pump‐ surgery reported contradictory results 14, 18, 19, 20, 21, 22…”
Section: Differences In Systemic Inflammatory Reaction and Platelet/cmentioning
confidence: 99%