An Open, Randomized, Controlled, Comparative Study of the Combined Effect of Intralesional Triamcinolone Acetonide and Onion Extract Gel and Intralesional Triamcinolone Acetonide Alone in the Treatment of Hypertrophic Scars and Keloids

Koç, Erol; Arca, Ercan; Sürücü, Barış; Kurumlu, Zafer

doi:10.1097/00042728-200811000-00013

Cited by 18 publications

(27 citation statements)

References 15 publications

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“…The better results witnessed by them was perhaps due to adjuvant surgical excision in addition to more frequent dosing at 2‐week intervals. Koc et al ., obtained an average change in height of 3.77 mm using triamcinolone acetonide alone, which was slightly better than our result of 3.16 mm . Similarly, Ahuja et al ., reported complete flattening in all the patients and a mean change in VSS as 7.04 .…”

Section: Discussionsupporting

confidence: 53%

A comparative study of various modalities in the treatment of keloids

et al. 2018

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Section: Discussionsupporting

confidence: 53%

A comparative study of various modalities in the treatment of keloids

et al. 2018

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“…TA injection is the standard treatment of hypertrophic scars and keloids as it inhibits the fibroblast overactivity. However, telangiectasia and residual erythema can occur after TA injection, and these complications are additional concerns for scar cosmesis . To ameliorate these problems, CBL was given to 30 patients in group 1 when TA injection was administered.…”

Section: Discussionmentioning

confidence: 99%

Risk factors for hypertrophic surgical scar development after thyroidectomy

Kim

Sung

Kim

et al. 2012

Wound Repair Regeneration

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Postoperative neck scarring is a major concern for patients who undergo thyroid surgery; however, the treatments for hypertrophic scars are generally considered by patients to provide unsatisfactory outcomes. Therefore, risk factors should be identified and prevention of these factors is considered to be critical in management. We reviewed the medical records of 96 thyroidectomy patients who were divided into two groups based on scar type: patients with hypertrophic (n = 61) and linear flat scars (n = 35). Multivariable logistic regression model was developed to identify risk factors for developing hypertrophic scar. There was no significant difference between the two groups in terms of age, gender ratio, tumor type, and type of operation. Multivariable analysis showed that hypertrophic scar development was associated with scars located within 1 cm above the sternal notch (odds ratio [OR] = 5.94, p = 0.01), prominent sternocleidomastoid muscles (OR = 12.03, p < 0.01), and a high body mass index (OR = 1.33, p = 0.01). The area under the receiver operating characteristic curve for risk factors was 0.85. Development of hypertrophic scar after thyroidectomy was found to be associated with specific preoperative factors such as incision site near the sternal notch, prominent sternocleidomastoid muscles, and high body mass index.

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“…A previous prospective, randomized, controlled trial had demonstrated that a topical preparation of onion extract, heparin, and allantoin can be effective in scar prevention after laser removal of tattoos 3 . Recent studies have demonstrated that a combination of onion extract and silicon sheet gel is more effective than occlusive silicon dressing in decreasing scar height 9 and that a combination of intralesional triamcinolone acetonide (TAC) and topical onion extract gel increases the therapeutic effect of TAC 10 …”

Section: Discussionmentioning

confidence: 99%