An open, prospective, randomized, multicenter study to compare recombinant human follicle stimulating hormone (rec-FSH; follitropin-β; Puregon® solution) with highly purified urinary FSH (uFSH, urofollitropin (highly purified), Metrodin® HP) in Chinese women undergoing   fertilization (IVF)

Twenty-two RCTs met the inclusion criteria: Fostimon(®) vs. Metrodin-HP(®) (n = 2); Fostimon(®) vs. recFSH (n = 8); and Metrodin-HP(®) vs. recFSH (n = 12). LBR (odds ratio = 1.72; 95% confidence interval = 1.05-2.80), OPR/LBR, and CPR were all significantly higher favoring Fostimon(®). OPR, MPR, OHSS, and miscarriage rates were not significantly different. Pooled results for cycle demographics were not reported due to high heterogeneity. Conclusions. Fostimon(®) is superior to Metrodin-HP(®) regarding clinical outcomes. Therefore, care should be taken not to assume that all hFSH products have the same efficacy.

show abstract

Are all human-derived follicle-stimulating hormone products the same? A systematic review and meta-analysis using direct and adjusted indirect analyses, to determine whether Fostimon ^® is more efficient than Metrodin-HP ^®

Al-Inany

Abou‐Setta

2011

Gynecological Endocrinology

View full text Add to dashboard Cite

show abstract

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

hi@scite.ai

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

An open, prospective, randomized, multicenter study to compare recombinant human follicle stimulating hormone (rec-FSH; follitropin-β; Puregon® solution) with highly purified urinary FSH (uFSH, urofollitropin (highly purified), Metrodin® HP) in Chinese women undergoing fertilization (IVF)

Cited by 1 publication

References 0 publications

Are all human-derived follicle-stimulating hormone products the same? A systematic review and meta-analysis using direct and adjusted indirect analyses, to determine whether Fostimon ^® is more efficient than Metrodin-HP ^®

Are all human-derived follicle-stimulating hormone products the same? A systematic review and meta-analysis using direct and adjusted indirect analyses, to determine whether Fostimon ^® is more efficient than Metrodin-HP ^®

Contact Info

Product

Resources

About

An open, prospective, randomized, multicenter study to compare recombinant human follicle stimulating hormone (rec-FSH; follitropin-β; Puregon® solution) with highly purified urinary FSH (uFSH, urofollitropin (highly purified), Metrodin® HP) in Chinese women undergoing fertilization (IVF)

Cited by 1 publication

References 0 publications

Are all human-derived follicle-stimulating hormone products the same? A systematic review and meta-analysis using direct and adjusted indirect analyses, to determine whether Fostimon ® is more efficient than Metrodin-HP ®

Are all human-derived follicle-stimulating hormone products the same? A systematic review and meta-analysis using direct and adjusted indirect analyses, to determine whether Fostimon ® is more efficient than Metrodin-HP ®

Contact Info

Product

Resources

About

Are all human-derived follicle-stimulating hormone products the same? A systematic review and meta-analysis using direct and adjusted indirect analyses, to determine whether Fostimon ^® is more efficient than Metrodin-HP ^®

Are all human-derived follicle-stimulating hormone products the same? A systematic review and meta-analysis using direct and adjusted indirect analyses, to determine whether Fostimon ^® is more efficient than Metrodin-HP ^®